Sorum AW - Search Results

1

Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity.

Shirakawa K, Wang L, Man N, Maksimoska J, Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E. Shirakawa K, et al. Among authors: sorum aw. Elife. 2016 May 31;5:e11156. doi: 10.7554/eLife.11156. Elife. 2016. PMID: 27244239 Free PMC article.

2

Defining the orphan functions of lysine acetyltransferases.

Montgomery DC, Sorum AW, Meier JL. Montgomery DC, et al. Among authors: sorum aw. ACS Chem Biol. 2015 Jan 16;10(1):85-94. doi: 10.1021/cb500853p. ACS Chem Biol. 2015. PMID: 25591746 Free PMC article. Review.

3

Defining Metabolic and Nonmetabolic Regulation of Histone Acetylation by NSAID Chemotypes.

Shrimp JH, Garlick JM, Tezil T, Sorum AW, Worth AJ, Blair IA, Verdin E, Snyder NW, Meier JL. Shrimp JH, et al. Among authors: sorum aw. Mol Pharm. 2018 Mar 5;15(3):729-736. doi: 10.1021/acs.molpharmaceut.7b00943. Epub 2017 Dec 29. Mol Pharm. 2018. PMID: 29240439 Free PMC article.

4

Chemoproteomic profiling of lysine acetyltransferases highlights an expanded landscape of catalytic acetylation.

Montgomery DC, Sorum AW, Meier JL. Montgomery DC, et al. Among authors: sorum aw. J Am Chem Soc. 2014 Jun 18;136(24):8669-76. doi: 10.1021/ja502372j. Epub 2014 May 30. J Am Chem Soc. 2014. PMID: 24836640 Free PMC article.

5

Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors.

Montgomery DC, Sorum AW, Guasch L, Nicklaus MC, Meier JL. Montgomery DC, et al. Among authors: sorum aw. Chem Biol. 2015 Aug 20;22(8):1030-1039. doi: 10.1016/j.chembiol.2015.06.015. Epub 2015 Jul 16. Chem Biol. 2015. PMID: 26190825 Free PMC article.

6

Characterizing the Covalent Targets of a Small Molecule Inhibitor of the Lysine Acetyltransferase P300.

Shrimp JH, Sorum AW, Garlick JM, Guasch L, Nicklaus MC, Meier JL. Shrimp JH, et al. Among authors: sorum aw. ACS Med Chem Lett. 2015 Oct 31;7(2):151-5. doi: 10.1021/acsmedchemlett.5b00385. eCollection 2016 Feb 11. ACS Med Chem Lett. 2015. PMID: 26985290 Free PMC article.

7

Microfluidic Mobility Shift Profiling of Lysine Acetyltransferases Enables Screening and Mechanistic Analysis of Cellular Acetylation Inhibitors.

Sorum AW, Shrimp JH, Roberts AM, Montgomery DC, Tiwari NK, Lal-Nag M, Simeonov A, Jadhav A, Meier JL. Sorum AW, et al. ACS Chem Biol. 2016 Mar 18;11(3):734-41. doi: 10.1021/acschembio.5b00709. Epub 2015 Oct 14. ACS Chem Biol. 2016. PMID: 26428393 Free PMC article.

8

Deciphering the Functions of O-GlcNAc Glycosylation in the Brain: The Role of Site-Specific Quantitative O-GlcNAcomics.

Thompson JW, Sorum AW, Hsieh-Wilson LC. Thompson JW, et al. Among authors: sorum aw. Biochemistry. 2018 Jul 10;57(27):4010-4018. doi: 10.1021/acs.biochem.8b00516. Epub 2018 Jul 2. Biochemistry. 2018. PMID: 29936833 Free PMC article.

9

Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs).

Rauch JN, Chen JJ, Sorum AW, Miller GM, Sharf T, See SK, Hsieh-Wilson LC, Kampmann M, Kosik KS. Rauch JN, et al. Among authors: sorum aw. Sci Rep. 2018 Apr 23;8(1):6382. doi: 10.1038/s41598-018-24904-z. Sci Rep. 2018. PMID: 29686391 Free PMC article.

10

Sulfated glycans engage the Ang-Tie pathway to regulate vascular development.

Griffin ME, Sorum AW, Miller GM, Goddard WA 3rd, Hsieh-Wilson LC. Griffin ME, et al. Among authors: sorum aw. Nat Chem Biol. 2021 Feb;17(2):178-186. doi: 10.1038/s41589-020-00657-7. Epub 2020 Oct 5. Nat Chem Biol. 2021. PMID: 33020664 Free PMC article.

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