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The vancomycin-nisin(1-12) hybrid restores activity against vancomycin resistant Enterococci.
Arnusch CJ, Bonvin AM, Verel AM, Jansen WT, Liskamp RM, de Kruijff B, Pieters RJ, Breukink E. Arnusch CJ, et al. Among authors: breukink e. Biochemistry. 2008 Dec 2;47(48):12661-3. doi: 10.1021/bi801597b. Biochemistry. 2008. PMID: 18989934
Lipid II is a crucial component in bacterial cell wall synthesis [Breukink, E., et al. (1999) Science 286, 2361-2364]. It is the target of a number of important antibiotics, which include vancomycin and nisin [Breukink, E., and de Kruijff, B. (2006) Na …
Lipid II is a crucial component in bacterial cell wall synthesis [Breukink, E., et al. (1999) Science 286, 2361-2364]. It is t …
Turning defense into offense: defensin mimetics as novel antibiotics targeting lipid II.
Varney KM, Bonvin AM, Pazgier M, Malin J, Yu W, Ateh E, Oashi T, Lu W, Huang J, Diepeveen-de Buin M, Bryant J, Breukink E, Mackerell AD Jr, de Leeuw EP. Varney KM, et al. Among authors: breukink e. PLoS Pathog. 2013;9(11):e1003732. doi: 10.1371/journal.ppat.1003732. Epub 2013 Nov 7. PLoS Pathog. 2013. PMID: 24244161 Free PMC article.
159 results