Wu X - Search Results

1

3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Decreases Hepatic and Systemic Ratios of Epoxide to Diol Metabolites of Unsaturated Fatty Acids in Male Rats.

Wu X, Yang J, Morisseau C, Robertson LW, Hammock B, Lehmler HJ. Wu X, et al. Toxicol Sci. 2016 Aug;152(2):309-22. doi: 10.1093/toxsci/kfw084. Epub 2016 May 13. Toxicol Sci. 2016. PMID: 27208083 Free PMC article.

2

2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) is enantioselectively oxidized to hydroxylated metabolites by rat liver microsomes.

Wu X, Pramanik A, Duffel MW, Hrycay EG, Bandiera SM, Lehmler HJ, Kania-Korwel I. Wu X, et al. Chem Res Toxicol. 2011 Dec 19;24(12):2249-57. doi: 10.1021/tx200360m. Epub 2011 Nov 10. Chem Res Toxicol. 2011. PMID: 22026639 Free PMC article.

3

Oxidation of polychlorinated biphenyls by liver tissue slices from phenobarbital-pretreated mice is congener-specific and atropselective.

Wu X, Duffel M, Lehmler HJ. Wu X, et al. Chem Res Toxicol. 2013 Nov 18;26(11):1642-51. doi: 10.1021/tx400229e. Epub 2013 Oct 23. Chem Res Toxicol. 2013. PMID: 24107130 Free PMC article.

4

Microsomal oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) results in species-dependent chiral signatures of the hydroxylated metabolites.

Wu X, Kammerer A, Lehmler HJ. Wu X, et al. Environ Sci Technol. 2014 Feb 18;48(4):2436-44. doi: 10.1021/es405433t. Epub 2014 Feb 5. Environ Sci Technol. 2014. PMID: 24467194 Free PMC article.

5

Effects of thiol antioxidants on the atropselective oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) by rat liver microsomes.

Wu X, Lehmler HJ. Wu X, et al. Environ Sci Pollut Res Int. 2016 Feb;23(3):2081-8. doi: 10.1007/s11356-015-4987-4. Epub 2015 Jul 9. Environ Sci Pollut Res Int. 2016. PMID: 26155892 Free PMC article.

6

Identification of lipidomic markers of chronic 3,3',4,4',5-pentachlorobiphenyl (PCB 126) exposure in the male rat liver.

Kania-Korwel I, Wu X, Wang K, Lehmler HJ. Kania-Korwel I, et al. Among authors: wu x. Toxicology. 2017 Sep 1;390:124-134. doi: 10.1016/j.tox.2017.09.005. Epub 2017 Sep 7. Toxicology. 2017. PMID: 28890136 Free PMC article.

7

Toxicokinetics of Chiral PCB 136 and Its Hydroxylated Metabolites in Mice with a Liver-Specific Deletion of Cytochrome P450 Reductase.

Li X, Wu X, Kelly KM, Veng-Pedersen P, Lehmler HJ. Li X, et al. Among authors: wu x. Chem Res Toxicol. 2019 Apr 15;32(4):727-736. doi: 10.1021/acs.chemrestox.8b00389. Epub 2019 Feb 20. Chem Res Toxicol. 2019. PMID: 30729780 Free PMC article.

8

Metabolism of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) atropisomers in tissue slices from phenobarbital or dexamethasone-induced rats is sex-dependent.

Wu X, Kania-Korwel I, Chen H, Stamou M, Dammanahalli KJ, Duffel M, Lein PJ, Lehmler HJ. Wu X, et al. Xenobiotica. 2013 Nov;43(11):933-47. doi: 10.3109/00498254.2013.785626. Epub 2013 Apr 12. Xenobiotica. 2013. PMID: 23581876 Free PMC article.

9

Cytochrome p450 mRNA expression in the rodent brain: species-, sex-, and region-dependent differences.

Stamou M, Wu X, Kania-Korwel I, Lehmler HJ, Lein PJ. Stamou M, et al. Among authors: wu x. Drug Metab Dispos. 2014 Feb;42(2):239-44. doi: 10.1124/dmd.113.054239. Epub 2013 Nov 19. Drug Metab Dispos. 2014. PMID: 24255117 Free PMC article.

10

Hepatic metabolism affects the atropselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice.

Wu X, Barnhart C, Lein PJ, Lehmler HJ. Wu X, et al. Environ Sci Technol. 2015 Jan 6;49(1):616-25. doi: 10.1021/es504766p. Epub 2014 Dec 10. Environ Sci Technol. 2015. PMID: 25420130 Free PMC article.

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