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Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing.
Sarett SM, Werfel TA, Chandra I, Jackson MA, Kavanaugh TE, Hattaway ME, Giorgio TD, Duvall CL. Sarett SM, et al. Among authors: jackson ma. Biomaterials. 2016 Aug;97:122-32. doi: 10.1016/j.biomaterials.2016.04.017. Epub 2016 Apr 21. Biomaterials. 2016. PMID: 27163624 Free PMC article.
Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers.
Jackson MA, Patel SS, Yu F, Cottam MA, Glass EB, Hoogenboezem EN, Fletcher RB, Dollinger BR, Patil P, Liu DD, Kelly IB, Bedingfield SK, King AR, Miles RE, Hasty AM, Giorgio TD, Duvall CL. Jackson MA, et al. Biomaterials. 2021 Jan;268:120528. doi: 10.1016/j.biomaterials.2020.120528. Epub 2020 Nov 23. Biomaterials. 2021. PMID: 33285438 Free PMC article.
Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.
Werfel TA, Wang S, Jackson MA, Kavanaugh TE, Joly MM, Lee LH, Hicks DJ, Sanchez V, Ericsson PG, Kilchrist KV, Dimobi SC, Sarett SM, Brantley-Sieders DM, Cook RS, Duvall CL. Werfel TA, et al. Among authors: jackson ma. Cancer Res. 2018 Apr 1;78(7):1845-1858. doi: 10.1158/0008-5472.CAN-17-2388. Epub 2018 Jan 22. Cancer Res. 2018. PMID: 29358172 Free PMC article.
511 results