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Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.
Vanderweyde T, Apicco DJ, Youmans-Kidder K, Ash PEA, Cook C, Lummertz da Rocha E, Jansen-West K, Frame AA, Citro A, Leszyk JD, Ivanov P, Abisambra JF, Steffen M, Li H, Petrucelli L, Wolozin B. Vanderweyde T, et al. Among authors: ash pea. Cell Rep. 2016 May 17;15(7):1455-1466. doi: 10.1016/j.celrep.2016.04.045. Epub 2016 May 6. Cell Rep. 2016. PMID: 27160897 Free PMC article.
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity.
Zhang YJ, Xu YF, Cook C, Gendron TF, Roettges P, Link CD, Lin WL, Tong J, Castanedes-Casey M, Ash P, Gass J, Rangachari V, Buratti E, Baralle F, Golde TE, Dickson DW, Petrucelli L. Zhang YJ, et al. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7607-12. doi: 10.1073/pnas.0900688106. Epub 2009 Apr 21. Proc Natl Acad Sci U S A. 2009. PMID: 19383787 Free PMC article.
Neurotoxic effects of TDP-43 overexpression in C. elegans.
Ash PE, Zhang YJ, Roberts CM, Saldi T, Hutter H, Buratti E, Petrucelli L, Link CD. Ash PE, et al. Hum Mol Genet. 2010 Aug 15;19(16):3206-18. doi: 10.1093/hmg/ddq230. Epub 2010 Jun 8. Hum Mol Genet. 2010. PMID: 20530643 Free PMC article.
Progressive amnestic dementia, hippocampal sclerosis, and mutation in C9ORF72.
Murray ME, Bieniek KF, Banks Greenberg M, DeJesus-Hernandez M, Rutherford NJ, van Blitterswijk M, Niemantsverdriet E, Ash PE, Gendron TF, Kouri N, Baker M, Goodman IJ, Petrucelli L, Rademakers R, Dickson DW. Murray ME, et al. Acta Neuropathol. 2013 Oct;126(4):545-54. doi: 10.1007/s00401-013-1161-2. Epub 2013 Aug 7. Acta Neuropathol. 2013. PMID: 23922030 Free PMC article.
Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS.
Gendron TF, Bieniek KF, Zhang YJ, Jansen-West K, Ash PE, Caulfield T, Daughrity L, Dunmore JH, Castanedes-Casey M, Chew J, Cosio DM, van Blitterswijk M, Lee WC, Rademakers R, Boylan KB, Dickson DW, Petrucelli L. Gendron TF, et al. Acta Neuropathol. 2013 Dec;126(6):829-44. doi: 10.1007/s00401-013-1192-8. Epub 2013 Oct 16. Acta Neuropathol. 2013. PMID: 24129584 Free PMC article.
Pathological stress granules in Alzheimer's disease.
Ash PE, Vanderweyde TE, Youmans KL, Apicco DJ, Wolozin B. Ash PE, et al. Brain Res. 2014 Oct 10;1584:52-8. doi: 10.1016/j.brainres.2014.05.052. Epub 2014 Aug 7. Brain Res. 2014. PMID: 25108040 Free PMC article.
31 results