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Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer.
Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. Vorvis C, et al. Among authors: iliopoulos d. Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1;310(11):G1124-37. doi: 10.1152/ajpgi.00035.2016. Epub 2016 May 5. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27151939 Free PMC article.
Functional role and therapeutic targeting of microRNAs in inflammatory bowel disease.
Soroosh A, Koutsioumpa M, Pothoulakis C, Iliopoulos D. Soroosh A, et al. Among authors: iliopoulos d. Am J Physiol Gastrointest Liver Physiol. 2018 Feb 1;314(2):G256-G262. doi: 10.1152/ajpgi.00268.2017. Epub 2017 Nov 16. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 29146677 Free PMC article. Review.
Sigmoid colon mucosal gene expression supports alterations of neuronal signaling in irritable bowel syndrome with constipation.
Videlock EJ, Mahurkar-Joshi S, Hoffman JM, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. Videlock EJ, et al. Among authors: iliopoulos d. Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1;315(1):G140-G157. doi: 10.1152/ajpgi.00288.2017. Epub 2018 Mar 22. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 29565640 Free PMC article.
MKAD-21 Suppresses the Oncogenic Activity of the miR-21/PPP2R2A/ERK Molecular Network in Bladder Cancer.
Koutsioumpa M, Chen HW, O'Brien N, Koinis F, Mahurkar-Joshi S, Vorvis C, Soroosh A, Luo T, Issakhanian S, Pantuck AJ, Georgoulias V, Iliopoulos D, Slamon DJ, Drakaki A. Koutsioumpa M, et al. Among authors: iliopoulos d. Mol Cancer Ther. 2018 Jul;17(7):1430-1440. doi: 10.1158/1535-7163.MCT-17-1049. Epub 2018 Apr 27. Mol Cancer Ther. 2018. PMID: 29703843
Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming.
Koutsioumpa M, Hatziapostolou M, Polytarchou C, Tolosa EJ, Almada LL, Mahurkar-Joshi S, Williams J, Tirado-Rodriguez AB, Huerta-Yepez S, Karavias D, Kourea H, Poultsides GA, Struhl K, Dawson DW, Donahue TR, Fernández-Zapico ME, Iliopoulos D. Koutsioumpa M, et al. Among authors: iliopoulos d. Gut. 2019 Jul;68(7):1271-1286. doi: 10.1136/gutjnl-2017-315690. Epub 2018 Oct 18. Gut. 2019. PMID: 30337373 Free PMC article.
miRNAs link metabolic reprogramming to oncogenesis.
Hatziapostolou M, Polytarchou C, Iliopoulos D. Hatziapostolou M, et al. Among authors: iliopoulos d. Trends Endocrinol Metab. 2013 Jul;24(7):361-73. doi: 10.1016/j.tem.2013.03.002. Epub 2013 Apr 19. Trends Endocrinol Metab. 2013. PMID: 23602813 Review.
MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice.
Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. Polytarchou C, et al. Among authors: iliopoulos d. Gastroenterology. 2015 Oct;149(4):981-92.e11. doi: 10.1053/j.gastro.2015.05.057. Epub 2015 Jun 6. Gastroenterology. 2015. PMID: 26055138 Free PMC article.
279 results