Gong N - Search Results

1

Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor.

Xie D, Lu J, Xie J, Cui J, Li TF, Wang YC, Chen Y, Gong N, Li XY, Fu L, Wang YX. Xie D, et al. Among authors: gong n. Eur J Med Chem. 2016 Jul 19;117:19-32. doi: 10.1016/j.ejmech.2016.04.017. Epub 2016 Apr 9. Eur J Med Chem. 2016. PMID: 27089209

2

A series of D-amino acid oxidase inhibitors specifically prevents and reverses formalin-induced tonic pain in rats.

Gong N, Gao ZY, Wang YC, Li XY, Huang JL, Hashimoto K, Wang YX. Gong N, et al. J Pharmacol Exp Ther. 2011 Jan;336(1):282-93. doi: 10.1124/jpet.110.172353. Epub 2010 Oct 15. J Pharmacol Exp Ther. 2011. PMID: 20952482

3

D-Amino acid oxidase-mediated increase in spinal hydrogen peroxide is mainly responsible for formalin-induced tonic pain.

Lu JM, Gong N, Wang YC, Wang YX. Lu JM, et al. Among authors: gong n. Br J Pharmacol. 2012 Mar;165(6):1941-1955. doi: 10.1111/j.1476-5381.2011.01680.x. Br J Pharmacol. 2012. PMID: 21950354 Free PMC article.

4

Interactions of the potent D-amino acid oxidase inhibitor CBIO with morphine in pain and tolerance to analgesia.

Gong N, Wang YC, Wang HL, Ma AN, Hashimoto K, Wang YX. Gong N, et al. Neuropharmacology. 2012 Sep;63(3):460-8. doi: 10.1016/j.neuropharm.2012.04.030. Epub 2012 May 2. Neuropharmacology. 2012. PMID: 22587944

5

Identification of a novel spinal dorsal horn astroglial D-amino acid oxidase-hydrogen peroxide pathway involved in morphine antinociceptive tolerance.

Gong N, Li XY, Xiao Q, Wang YX. Gong N, et al. Anesthesiology. 2014 Apr;120(4):962-75. doi: 10.1097/ALN.0b013e3182a66d2a. Anesthesiology. 2014. PMID: 23928652 Free article.

6

Contributions of spinal D-amino acid oxidase to chronic morphine-induced hyperalgesia.

Ma S, Li XY, Gong N, Wang YX. Ma S, et al. Among authors: gong n. J Pharm Biomed Anal. 2015 Dec 10;116:131-8. doi: 10.1016/j.jpba.2015.03.021. Epub 2015 Mar 28. J Pharm Biomed Anal. 2015. PMID: 25850373

7

Spinal D-amino acid oxidase contributes to mechanical pain hypersensitivity induced by sleep deprivation in the rat.

Wei H, Gong N, Huang JL, Fan H, Ma AN, Li XY, Wang YX, Pertovaara A. Wei H, et al. Among authors: gong n. Pharmacol Biochem Behav. 2013 Oct;111:30-6. doi: 10.1016/j.pbb.2013.08.003. Epub 2013 Aug 17. Pharmacol Biochem Behav. 2013. PMID: 23958579

8

Shanzhiside methylester, the principle effective iridoid glycoside from the analgesic herb Lamiophlomis rotata, reduces neuropathic pain by stimulating spinal microglial β-endorphin expression.

Fan H, Li TF, Gong N, Wang YX. Fan H, et al. Among authors: gong n. Neuropharmacology. 2016 Feb;101:98-109. doi: 10.1016/j.neuropharm.2015.09.010. Epub 2015 Sep 9. Neuropharmacology. 2016. PMID: 26363192

9

Dezocine exhibits antihypersensitivity activities in neuropathy through spinal μ-opioid receptor activation and norepinephrine reuptake inhibition.

Wang YX, Mao XF, Li TF, Gong N, Zhang MZ. Wang YX, et al. Among authors: gong n. Sci Rep. 2017 Feb 23;7:43137. doi: 10.1038/srep43137. Sci Rep. 2017. PMID: 28230181 Free PMC article.

10

Indispensable but insufficient role of renal D-amino acid oxidase in chiral inversion of NG-nitro-D-arginine.

Xin YF, Li X, Hao B, Gong N, Sun WQ, Konno R, Wang YX. Xin YF, et al. Among authors: gong n. Chem Biodivers. 2010 Jun;7(6):1413-23. doi: 10.1002/cbdv.200900275. Chem Biodivers. 2010. PMID: 20564560

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