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Page 1
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis.
Nielsen SR, Quaranta V, Linford A, Emeagi P, Rainer C, Santos A, Ireland L, Sakai T, Sakai K, Kim YS, Engle D, Campbell F, Palmer D, Ko JH, Tuveson DA, Hirsch E, Mielgo A, Schmid MC. Nielsen SR, et al. Among authors: tuveson da. Nat Cell Biol. 2016 May;18(5):549-60. doi: 10.1038/ncb3340. Epub 2016 Apr 18. Nat Cell Biol. 2016. PMID: 27088855 Free PMC article.
The pancreas cancer microenvironment.
Feig C, Gopinathan A, Neesse A, Chan DS, Cook N, Tuveson DA. Feig C, et al. Among authors: tuveson da. Clin Cancer Res. 2012 Aug 15;18(16):4266-76. doi: 10.1158/1078-0432.CCR-11-3114. Clin Cancer Res. 2012. PMID: 22896693 Free PMC article. Review.
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.
Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, Shimosegawa T, Apte MV, Wilson JS, Ng B, Lau SL, Gunton JE, Wahl GM, Hunter T, Drebin JA, O'Dwyer PJ, Liddle C, Tuveson DA, Downes M, Evans RM. Sherman MH, et al. Among authors: tuveson da. Cell. 2014 Sep 25;159(1):80-93. doi: 10.1016/j.cell.2014.08.007. Cell. 2014. PMID: 25259922 Free PMC article.
p53 mutations change phosphatidylinositol acyl chain composition.
Naguib A, Bencze G, Engle DD, Chio II, Herzka T, Watrud K, Bencze S, Tuveson DA, Pappin DJ, Trotman LC. Naguib A, et al. Among authors: tuveson da. Cell Rep. 2015 Jan 6;10(1):8-19. doi: 10.1016/j.celrep.2014.12.010. Epub 2014 Dec 24. Cell Rep. 2015. PMID: 25543136 Free PMC article.
Organoid models of human and mouse ductal pancreatic cancer.
Boj SF, Hwang CI, Baker LA, Chio II, Engle DD, Corbo V, Jager M, Ponz-Sarvise M, Tiriac H, Spector MS, Gracanin A, Oni T, Yu KH, van Boxtel R, Huch M, Rivera KD, Wilson JP, Feigin ME, Öhlund D, Handly-Santana A, Ardito-Abraham CM, Ludwig M, Elyada E, Alagesan B, Biffi G, Yordanov GN, Delcuze B, Creighton B, Wright K, Park Y, Morsink FH, Molenaar IQ, Borel Rinkes IH, Cuppen E, Hao Y, Jin Y, Nijman IJ, Iacobuzio-Donahue C, Leach SD, Pappin DJ, Hammell M, Klimstra DS, Basturk O, Hruban RH, Offerhaus GJ, Vries RG, Clevers H, Tuveson DA. Boj SF, et al. Among authors: tuveson da. Cell. 2015 Jan 15;160(1-2):324-38. doi: 10.1016/j.cell.2014.12.021. Epub 2014 Dec 31. Cell. 2015. PMID: 25557080 Free PMC article.
ADAM8 as a drug target in pancreatic cancer.
Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia AM, Höfling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem RR, Moss ML, Rasmussen FH, Miller MA, Lauffenburger DA, Tuveson DA, Nimsky C, Bartsch JW. Schlomann U, et al. Among authors: tuveson da. Nat Commun. 2015 Jan 28;6:6175. doi: 10.1038/ncomms7175. Nat Commun. 2015. PMID: 25629724 Free PMC article.
Preclinical models of pancreatic ductal adenocarcinoma.
Hwang CI, Boj SF, Clevers H, Tuveson DA. Hwang CI, et al. Among authors: tuveson da. J Pathol. 2016 Jan;238(2):197-204. doi: 10.1002/path.4651. Epub 2015 Nov 14. J Pathol. 2016. PMID: 26419819 Free PMC article. Review.
TLR9 ligation in pancreatic stellate cells promotes tumorigenesis.
Zambirinis CP, Levie E, Nguy S, Avanzi A, Barilla R, Xu Y, Seifert L, Daley D, Greco SH, Deutsch M, Jonnadula S, Torres-Hernandez A, Tippens D, Pushalkar S, Eisenthal A, Saxena D, Ahn J, Hajdu C, Engle DD, Tuveson D, Miller G. Zambirinis CP, et al. J Exp Med. 2015 Nov 16;212(12):2077-94. doi: 10.1084/jem.20142162. Epub 2015 Oct 19. J Exp Med. 2015. PMID: 26481685 Free PMC article.
Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus.
Jenkinson C, Elliott VL, Evans A, Oldfield L, Jenkins RE, O'Brien DP, Apostolidou S, Gentry-Maharaj A, Fourkala EO, Jacobs IJ, Menon U, Cox T, Campbell F, Pereira SP, Tuveson DA, Park BK, Greenhalf W, Sutton R, Timms JF, Neoptolemos JP, Costello E. Jenkinson C, et al. Among authors: tuveson da. Clin Cancer Res. 2016 Apr 1;22(7):1734-1743. doi: 10.1158/1078-0432.CCR-15-0879. Epub 2015 Nov 16. Clin Cancer Res. 2016. PMID: 26573598 Free PMC article.
248 results