Nolan EM - Search Results

1

Proteolysis Triggers Self-Assembly and Unmasks Innate Immune Function of a Human α-Defensin Peptide.

Chairatana P, Chu H, Castillo PA, Shen B, Bevins CL, Nolan EM. Chairatana P, et al. Among authors: nolan em. Chem Sci. 2016 Mar 1;7(3):1738-1752. doi: 10.1039/C5SC04194E. Epub 2015 Dec 10. Chem Sci. 2016. PMID: 27076903 Free PMC article.

2

Reduction of human defensin 5 affords a high-affinity zinc-chelating peptide.

Zhang Y, Cougnon FB, Wanniarachchi YA, Hayden JA, Nolan EM. Zhang Y, et al. Among authors: nolan em. ACS Chem Biol. 2013 Sep 20;8(9):1907-11. doi: 10.1021/cb400340k. Epub 2013 Jul 10. ACS Chem Biol. 2013. PMID: 23841778 Free PMC article.

3

Molecular basis for self-assembly of a human host-defense peptide that entraps bacterial pathogens.

Chairatana P, Nolan EM. Chairatana P, et al. Among authors: nolan em. J Am Chem Soc. 2014 Sep 24;136(38):13267-76. doi: 10.1021/ja5057906. Epub 2014 Sep 12. J Am Chem Soc. 2014. PMID: 25158166 Free PMC article.

4

Discovery and characterization of a disulfide-locked C(2)-symmetric defensin peptide.

Wommack AJ, Ziarek JJ, Tomaras J, Chileveru HR, Zhang Y, Wagner G, Nolan EM. Wommack AJ, et al. Among authors: nolan em. J Am Chem Soc. 2014 Oct 1;136(39):13494-7. doi: 10.1021/ja505957w. Epub 2014 Sep 23. J Am Chem Soc. 2014. PMID: 25181039 Free PMC article.

5

A bacterial mutant library as a tool to study the attack of a defensin peptide.

Moser S, Chileveru HR, Tomaras J, Nolan EM. Moser S, et al. Among authors: nolan em. Chembiochem. 2014 Dec 15;15(18):2684-8. doi: 10.1002/cbic.201402354. Epub 2014 Nov 27. Chembiochem. 2014. PMID: 25430675 Free PMC article.

6

Visualizing attack of Escherichia coli by the antimicrobial peptide human defensin 5.

Chileveru HR, Lim SA, Chairatana P, Wommack AJ, Chiang IL, Nolan EM. Chileveru HR, et al. Among authors: nolan em. Biochemistry. 2015 Mar 10;54(9):1767-77. doi: 10.1021/bi501483q. Epub 2015 Mar 2. Biochemistry. 2015. PMID: 25664683 Free PMC article.

7

Calcium Ions Tune the Zinc-Sequestering Properties and Antimicrobial Activity of Human S100A12.

Cunden LS, Gaillard A, Nolan EM. Cunden LS, et al. Among authors: nolan em. Chem Sci. 2016 Feb 1;7(2):1338-1348. doi: 10.1039/C5SC03655K. Epub 2015 Oct 26. Chem Sci. 2016. PMID: 26913170 Free PMC article.

8

Calcium-induced Tetramerization and Zinc Chelation Shield Human Calprotectin from Degradation by Host and Bacterial Extracellular Proteases.

Stephan JR, Nolan EM. Stephan JR, et al. Among authors: nolan em. Chem Sci. 2016 Mar 1;7(3):1962-1975. doi: 10.1039/C5SC03287C. Epub 2015 Nov 23. Chem Sci. 2016. PMID: 26925211 Free PMC article.

9

Siderophore-based immunization strategy to inhibit growth of enteric pathogens.

Sassone-Corsi M, Chairatana P, Zheng T, Perez-Lopez A, Edwards RA, George MD, Nolan EM, Raffatellu M. Sassone-Corsi M, et al. Among authors: nolan em. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13462-13467. doi: 10.1073/pnas.1606290113. Epub 2016 Nov 7. Proc Natl Acad Sci U S A. 2016. PMID: 27821741 Free PMC article.

10

Defensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut.

Chairatana P, Nolan EM. Chairatana P, et al. Among authors: nolan em. Crit Rev Biochem Mol Biol. 2017 Feb;52(1):45-56. doi: 10.1080/10409238.2016.1243654. Epub 2016 Nov 13. Crit Rev Biochem Mol Biol. 2017. PMID: 27841019 Free PMC article. Review.

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