Li J - Search Results

1

Discovery of 7-Methyl-10-Hydroxyhomocamptothecins with 1,2,3-Triazole Moiety as Potent Topoisomerase I Inhibitors.

Xu X, Wu Y, Liu W, Sheng C, Yao J, Dong G, Fang K, Li J, Yu Z, Min X, Zhang H, Miao Z, Zhang W. Xu X, et al. Among authors: li j. Chem Biol Drug Des. 2016 Sep;88(3):398-403. doi: 10.1111/cbdd.12767. Epub 2016 May 5. Chem Biol Drug Des. 2016. PMID: 27062430

2

Design, synthesis and biological evaluation of sulfamide and triazole benzodiazepines as novel p53-MDM2 inhibitors.

Yu Z, Zhuang C, Wu Y, Guo Z, Li J, Dong G, Yao J, Sheng C, Miao Z, Zhang W. Yu Z, et al. Among authors: li j. Int J Mol Sci. 2014 Sep 5;15(9):15741-53. doi: 10.3390/ijms150915741. Int J Mol Sci. 2014. PMID: 25198897 Free PMC article.

3

Discovery of 1-arylpyrrolidone derivatives as potent p53-MDM2 inhibitors based on molecule fusing strategy.

Li J, Wu Y, Guo Z, Zhuang C, Yao J, Dong G, Yu Z, Min X, Wang S, Liu Y, Wu S, Zhu S, Sheng C, Miao Z, Zhang W. Li J, et al. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2648-50. doi: 10.1016/j.bmcl.2014.04.063. Epub 2014 Apr 26. Bioorg Med Chem Lett. 2014. PMID: 24813735

4

Design, synthesis and biological activity of piperlongumine derivatives as selective anticancer agents.

Wu Y, Min X, Zhuang C, Li J, Yu Z, Dong G, Yao J, Wang S, Liu Y, Wu S, Zhu S, Sheng C, Wei Y, Zhang H, Zhang W, Miao Z. Wu Y, et al. Among authors: li j. Eur J Med Chem. 2014 Jul 23;82:545-51. doi: 10.1016/j.ejmech.2014.05.070. Epub 2014 Jun 2. Eur J Med Chem. 2014. PMID: 24937186

5

A fluorescent probe for imaging p53-MDM2 protein-protein interaction.

Liu Z, Miao Z, Li J, Fang K, Zhuang C, Du L, Sheng C, Li M. Liu Z, et al. Among authors: li j, li m. Chem Biol Drug Des. 2015 Apr;85(4):411-7. doi: 10.1111/cbdd.12434. Epub 2014 Oct 10. Chem Biol Drug Des. 2015. PMID: 25226874

6

Double-edged swords as cancer therapeutics: novel, orally active, small molecules simultaneously inhibit p53-MDM2 interaction and the NF-κB pathway.

Zhuang C, Miao Z, Wu Y, Guo Z, Li J, Yao J, Xing C, Sheng C, Zhang W. Zhuang C, et al. Among authors: li j. J Med Chem. 2014 Feb 13;57(3):567-77. doi: 10.1021/jm401800k. Epub 2014 Jan 24. J Med Chem. 2014. PMID: 24428757

7

A novel drug discovery strategy: mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-κB pathways.

Zhuang C, Sheng C, Shin WS, Wu Y, Li J, Yao J, Dong G, Zhang W, Sham YY, Miao Z, Zhang W. Zhuang C, et al. Among authors: li j. Oncotarget. 2014 Nov 15;5(21):10830-9. doi: 10.18632/oncotarget.2521. Oncotarget. 2014. PMID: 25350970 Free PMC article.

8

Environment-sensitive turn-on fluorescent probes for p53-MDM2 protein-protein interaction.

Liu T, Jiang Y, Liu Z, Li J, Fang K, Zhuang C, Du L, Fang H, Sheng C, Li M. Liu T, et al. Among authors: li j, li m. Medchemcomm. 2017 Jul 3;8(8):1668-1672. doi: 10.1039/c7md00287d. eCollection 2017 Aug 1. Medchemcomm. 2017. PMID: 30108877 Free PMC article.

9

Correction: Environment-sensitive turn-on fluorescent probes for p53-MDM2 protein-protein interaction.

Liu T, Jiang Y, Liu Z, Li J, Fang K, Zhuang C, Du L, Fang H, Sheng C, Li M. Liu T, et al. Among authors: li j, li m. Medchemcomm. 2017 Aug 1;8(8):1727. doi: 10.1039/c7md90031g. eCollection 2017 Aug 1. Medchemcomm. 2017. PMID: 30109865 Free PMC article.

10

Pharmacophore hybridisation and nanoscale assembly to discover self-delivering lysosomotropic new-chemical entities for cancer therapy.

Ma Z, Li J, Lin K, Ramachandran M, Zhang D, Showalter M, De Souza C, Lindstrom A, Solano LN, Jia B, Urayama S, Duan Y, Fiehn O, Lin TY, Li M, Li Y. Ma Z, et al. Among authors: li y, li j, li m. Nat Commun. 2020 Sep 15;11(1):4615. doi: 10.1038/s41467-020-18399-4. Nat Commun. 2020. PMID: 32934241 Free PMC article.

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