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Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival.
Kloepper J, Riedemann L, Amoozgar Z, Seano G, Susek K, Yu V, Dalvie N, Amelung RL, Datta M, Song JW, Askoxylakis V, Taylor JW, Lu-Emerson C, Batista A, Kirkpatrick ND, Jung K, Snuderl M, Muzikansky A, Stubenrauch KG, Krieter O, Wakimoto H, Xu L, Munn LL, Duda DG, Fukumura D, Batchelor TT, Jain RK. Kloepper J, et al. Among authors: lu emerson c. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4476-81. doi: 10.1073/pnas.1525360113. Epub 2016 Apr 4. Proc Natl Acad Sci U S A. 2016. PMID: 27044098 Free PMC article.
Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma.
Lu-Emerson C, Snuderl M, Kirkpatrick ND, Goveia J, Davidson C, Huang Y, Riedemann L, Taylor J, Ivy P, Duda DG, Ancukiewicz M, Plotkin SR, Chi AS, Gerstner ER, Eichler AF, Dietrich J, Stemmer-Rachamimov AO, Batchelor TT, Jain RK. Lu-Emerson C, et al. Neuro Oncol. 2013 Aug;15(8):1079-87. doi: 10.1093/neuonc/not082. Epub 2013 Jul 4. Neuro Oncol. 2013. PMID: 23828240 Free PMC article.
Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation.
Batchelor TT, Gerstner ER, Emblem KE, Duda DG, Kalpathy-Cramer J, Snuderl M, Ancukiewicz M, Polaskova P, Pinho MC, Jennings D, Plotkin SR, Chi AS, Eichler AF, Dietrich J, Hochberg FH, Lu-Emerson C, Iafrate AJ, Ivy SP, Rosen BR, Loeffler JS, Wen PY, Sorensen AG, Jain RK. Batchelor TT, et al. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19059-64. doi: 10.1073/pnas.1318022110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24190997 Free PMC article. Clinical Trial.
Brain metastases.
Lu-Emerson C, Eichler AF. Lu-Emerson C, et al. Continuum (Minneap Minn). 2012 Apr;18(2):295-311. doi: 10.1212/01.CON.0000413659.12304.a6. Continuum (Minneap Minn). 2012. PMID: 22810128 Review.
The Neurofibromatoses. Part 1: NF1.
Lu-Emerson C, Plotkin SR. Lu-Emerson C, et al. Rev Neurol Dis. 2009 Spring;6(2):E47-53. Rev Neurol Dis. 2009. PMID: 19587630 Review.
20 results