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Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.
Derkinderen P, Scales TM, Hanger DP, Leung KY, Byers HL, Ward MA, Lenz C, Price C, Bird IN, Perera T, Kellie S, Williamson R, Noble W, Van Etten RA, Leroy K, Brion JP, Reynolds CH, Anderton BH. Derkinderen P, et al. Among authors: noble w. J Neurosci. 2005 Jul 13;25(28):6584-93. doi: 10.1523/JNEUROSCI.1487-05.2005. J Neurosci. 2005. PMID: 16014719 Free PMC article.
Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression.
Cole AR, Noble W, van Aalten L, Plattner F, Meimaridou R, Hogan D, Taylor M, LaFrancois J, Gunn-Moore F, Verkhratsky A, Oddo S, LaFerla F, Giese KP, Dineley KT, Duff K, Richardson JC, Yan SD, Hanger DP, Allan SM, Sutherland C. Cole AR, et al. Among authors: noble w. J Neurochem. 2007 Nov;103(3):1132-44. doi: 10.1111/j.1471-4159.2007.04829.x. Epub 2007 Aug 7. J Neurochem. 2007. PMID: 17683481 Free article.
The microtubule-associated protein tau is also phosphorylated on tyrosine.
Lebouvier T, Scales TM, Williamson R, Noble W, Duyckaerts C, Hanger DP, Reynolds CH, Anderton BH, Derkinderen P. Lebouvier T, et al. Among authors: noble w. J Alzheimers Dis. 2009;18(1):1-9. doi: 10.3233/JAD-2009-1116. J Alzheimers Dis. 2009. PMID: 19542604 Review.
824 results