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An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells.
Knies D, Klobuch S, Xue SA, Birtel M, Echchannaoui H, Yildiz O, Omokoko T, Guillaume P, Romero P, Stauss H, Sahin U, Herr W, Theobald M, Thomas S, Voss RH. Knies D, et al. Among authors: thomas s. Oncotarget. 2016 Apr 19;7(16):21199-221. doi: 10.18632/oncotarget.8385. Oncotarget. 2016. PMID: 27028870 Free PMC article.
Alloreactive and leukemia-reactive T cells are preferentially derived from naive precursors in healthy donors: implications for immunotherapy with memory T cells.
Distler E, Bloetz A, Albrecht J, Asdufan S, Hohberger A, Frey M, Schnürer E, Thomas S, Theobald M, Hartwig UF, Herr W. Distler E, et al. Among authors: thomas s. Haematologica. 2011 Jul;96(7):1024-32. doi: 10.3324/haematol.2010.037481. Epub 2011 Apr 12. Haematologica. 2011. PMID: 21486863 Free PMC article.
Varicella-zoster virus glycoproteins B and E are major targets of CD4+ and CD8+ T cells reconstituting during zoster after allogeneic transplantation.
Kleemann P, Distler E, Wagner EM, Thomas S, Klobuch S, Aue S, Schnürer E, Schild H, Theobald M, Plachter B, Tenzer S, Meyer RG, Herr W. Kleemann P, et al. Among authors: thomas s. Haematologica. 2012 Jun;97(6):874-82. doi: 10.3324/haematol.2011.052597. Epub 2011 Dec 29. Haematologica. 2012. PMID: 22207687 Free PMC article.
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