Weber A - Search Results

1

The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis.

Weber A, Heinlein M, Dengjel J, Alber C, Singh PK, Häcker G. Weber A, et al. EMBO Rep. 2016 May;17(5):724-38. doi: 10.15252/embr.201541392. Epub 2016 Mar 24. EMBO Rep. 2016. PMID: 27013495 Free PMC article.

2

BH3-only proteins trigger cytochrome c release, but how?

Häcker G, Weber A. Häcker G, et al. Among authors: weber a. Arch Biochem Biophys. 2007 Jun 15;462(2):150-5. doi: 10.1016/j.abb.2006.12.022. Epub 2007 Jan 9. Arch Biochem Biophys. 2007. PMID: 17306210 Review.

3

BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins.

Weber A, Paschen SA, Heger K, Wilfling F, Frankenberg T, Bauerschmitt H, Seiffert BM, Kirschnek S, Wagner H, Häcker G. Weber A, et al. J Cell Biol. 2007 May 21;177(4):625-36. doi: 10.1083/jcb.200610148. J Cell Biol. 2007. PMID: 17517961 Free PMC article.

4

Mitochondrial protein import: a matter of death?

Paschen SA, Weber A, Häcker G. Paschen SA, et al. Among authors: weber a. Cell Cycle. 2007 Oct 15;6(20):2434-9. doi: 10.4161/cc.6.20.4780. Epub 2007 Jul 23. Cell Cycle. 2007. PMID: 17726377

5

Endogenous Noxa Determines the Strong Proapoptotic Synergism of the BH3-Mimetic ABT-737 with Chemotherapeutic Agents in Human Melanoma Cells.

Weber A, Kirejczyk Z, Potthoff S, Ploner C, Häcker G. Weber A, et al. Transl Oncol. 2009 May;2(2):73-83. doi: 10.1593/tlo.08223. Transl Oncol. 2009. PMID: 19412422 Free PMC article.

6

Toxoplasma gondii infection confers resistance against BimS-induced apoptosis by preventing the activation and mitochondrial targeting of pro-apoptotic Bax.

Hippe D, Weber A, Zhou L, Chang DC, Häcker G, Lüder CG. Hippe D, et al. Among authors: weber a. J Cell Sci. 2009 Oct 1;122(Pt 19):3511-21. doi: 10.1242/jcs.050963. Epub 2009 Sep 8. J Cell Sci. 2009. PMID: 19737817

7

Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells.

Weber A, Kirejczyk Z, Besch R, Potthoff S, Leverkus M, Häcker G. Weber A, et al. Cell Death Differ. 2010 Jun;17(6):942-51. doi: 10.1038/cdd.2009.190. Epub 2009 Dec 18. Cell Death Differ. 2010. PMID: 20019748

8

Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1.

Zall H, Weber A, Besch R, Zantl N, Häcker G. Zall H, et al. Among authors: weber a. Mol Cancer. 2010 Jun 24;9:164. doi: 10.1186/1476-4598-9-164. Mol Cancer. 2010. PMID: 20576107 Free PMC article.

9

BH3-only proteins are tail-anchored in the outer mitochondrial membrane and can initiate the activation of Bax.

Wilfling F, Weber A, Potthoff S, Vögtle FN, Meisinger C, Paschen SA, Häcker G. Wilfling F, et al. Among authors: weber a. Cell Death Differ. 2012 Aug;19(8):1328-36. doi: 10.1038/cdd.2012.9. Epub 2012 Feb 17. Cell Death Differ. 2012. PMID: 22343714 Free PMC article.

10

Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.

Weber A, Ausländer D, Häcker G. Weber A, et al. Apoptosis. 2013 Sep;18(9):1093-105. doi: 10.1007/s10495-013-0868-9. Apoptosis. 2013. PMID: 23733106

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