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The CT20 peptide causes detachment and death of metastatic breast cancer cells by promoting mitochondrial aggregation and cytoskeletal disruption.
Lee MW, Bassiouni R, Sparrow NA, Iketani A, Boohaker RJ, Moskowitz C, Vishnubhotla P, Khaled AS, Oyer J, Copik A, Fernandez-Valle C, Perez JM, Khaled AR. Lee MW, et al. Among authors: perez jm. Cell Death Dis. 2014 May 22;5(5):e1249. doi: 10.1038/cddis.2014.225. Cell Death Dis. 2014. PMID: 24853427 Free PMC article.
Rational development of a cytotoxic peptide to trigger cell death.
Boohaker RJ, Zhang G, Lee MW, Nemec KN, Santra S, Perez JM, Khaled AR. Boohaker RJ, et al. Among authors: perez jm. Mol Pharm. 2012 Jul 2;9(7):2080-93. doi: 10.1021/mp300167e. Epub 2012 May 29. Mol Pharm. 2012. PMID: 22591113 Free PMC article.
PSMA-Targeted Theranostic Nanocarrier for Prostate Cancer.
Flores O, Santra S, Kaittanis C, Bassiouni R, Khaled AS, Khaled AR, Grimm J, Perez JM. Flores O, et al. Among authors: perez jm. Theranostics. 2017 Jun 24;7(9):2477-2494. doi: 10.7150/thno.18879. eCollection 2017. Theranostics. 2017. PMID: 28744329 Free PMC article.
The use of therapeutic peptides to target and to kill cancer cells.
Boohaker RJ, Lee MW, Vishnubhotla P, Perez JM, Khaled AR. Boohaker RJ, et al. Among authors: perez jm. Curr Med Chem. 2012;19(22):3794-804. doi: 10.2174/092986712801661004. Curr Med Chem. 2012. PMID: 22725698 Free PMC article. Review.
553 results