TPEN, a Specific Zn2+ Chelator, Inhibits Sodium Dithionite and Glucose Deprivation (SDGD)-Induced Neuronal Death by Modulating Apoptosis, Glutamate Signaling, and Voltage-Gated K+ and Na+ Channels.
Zhang F, Ma XL, Wang YX, He CC, Tian K, Wang HG, An D, Heng B, Xie LH, Liu YQ.
Zhang F, et al. Among authors: an d.
Cell Mol Neurobiol. 2017 Mar;37(2):235-250. doi: 10.1007/s10571-016-0364-1. Epub 2016 Mar 16.
Cell Mol Neurobiol. 2017.
PMID: 26983717
Hypoxia-ischemia-induced neuronal death is an important pathophysiological process that accompanies ischemic stroke and represents a major challenge in preventing ischemic stroke. ...The effects of N,N,N',N'-tetrakis (2-pyridylmethyl) ethylenediamine (TPEN), a specific Zn( …
Hypoxia-ischemia-induced neuronal death is an important pathophysiological process that accompanies ischemic stroke and represents a …