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Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype.
Gabrusiewicz K, Rodriguez B, Wei J, Hashimoto Y, Healy LM, Maiti SN, Thomas G, Zhou S, Wang Q, Elakkad A, Liebelt BD, Yaghi NK, Ezhilarasan R, Huang N, Weinberg JS, Prabhu SS, Rao G, Sawaya R, Langford LA, Bruner JM, Fuller GN, Bar-Or A, Li W, Colen RR, Curran MA, Bhat KP, Antel JP, Cooper LJ, Sulman EP, Heimberger AB. Gabrusiewicz K, et al. Among authors: curran ma. JCI Insight. 2016;1(2):e85841. doi: 10.1172/jci.insight.85841. Epub 2016 Feb 25. JCI Insight. 2016. PMID: 26973881 Free PMC article.
Anti-PD-1 Induces M1 Polarization in the Glioma Microenvironment and Exerts Therapeutic Efficacy in the Absence of CD8 Cytotoxic T Cells.
Rao G, Latha K, Ott M, Sabbagh A, Marisetty A, Ling X, Zamler D, Doucette TA, Yang Y, Kong LY, Wei J, Fuller GN, Benavides F, Sonabend AM, Long J, Li S, Curran M, Heimberger AB. Rao G, et al. Clin Cancer Res. 2020 Sep 1;26(17):4699-4712. doi: 10.1158/1078-0432.CCR-19-4110. Epub 2020 Jun 18. Clin Cancer Res. 2020. PMID: 32554515 Free PMC article.
Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration.
Ott M, Tomaszowski KH, Marisetty A, Kong LY, Wei J, Duna M, Blumberg K, Ji X, Jacobs C, Fuller GN, Langford LA, Huse JT, Long JP, Hu J, Li S, Weinberg JS, Prabhu SS, Sawaya R, Ferguson S, Rao G, Lang FF, Curran MA, Heimberger AB. Ott M, et al. Among authors: curran ma. JCI Insight. 2020 Sep 3;5(17):e134386. doi: 10.1172/jci.insight.134386. JCI Insight. 2020. PMID: 32721947 Free PMC article.
Opening of the Blood-Brain Barrier Using Low-Intensity Pulsed Ultrasound Enhances Responses to Immunotherapy in Preclinical Glioma Models.
Sabbagh A, Beccaria K, Ling X, Marisetty A, Ott M, Caruso H, Barton E, Kong LY, Fang D, Latha K, Zhang DY, Wei J, DeGroot J, Curran MA, Rao G, Hu J, Desseaux C, Bouchoux G, Canney M, Carpentier A, Heimberger AB. Sabbagh A, et al. Among authors: curran ma. Clin Cancer Res. 2021 Aug 1;27(15):4325-4337. doi: 10.1158/1078-0432.CCR-20-3760. Epub 2021 May 24. Clin Cancer Res. 2021. PMID: 34031054 Free PMC article.
150 results