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Structural hot spots for the solubility of globular proteins.
Ganesan A, Siekierska A, Beerten J, Brams M, Van Durme J, De Baets G, Van der Kant R, Gallardo R, Ramakers M, Langenberg T, Wilkinson H, De Smet F, Ulens C, Rousseau F, Schymkowitz J. Ganesan A, et al. Among authors: van der kant r, van durme j. Nat Commun. 2016 Feb 24;7:10816. doi: 10.1038/ncomms10816. Nat Commun. 2016. PMID: 26905391 Free PMC article.
Solubis: optimize your protein.
De Baets G, Van Durme J, van der Kant R, Schymkowitz J, Rousseau F. De Baets G, et al. Among authors: van der kant r, van durme j. Bioinformatics. 2015 Aug 1;31(15):2580-2. doi: 10.1093/bioinformatics/btv162. Epub 2015 Mar 19. Bioinformatics. 2015. PMID: 25792555
Solubis: a webserver to reduce protein aggregation through mutation.
Van Durme J, De Baets G, Van Der Kant R, Ramakers M, Ganesan A, Wilkinson H, Gallardo R, Rousseau F, Schymkowitz J. Van Durme J, et al. Among authors: van der kant r. Protein Eng Des Sel. 2016 Aug;29(8):285-9. doi: 10.1093/protein/gzw019. Epub 2016 Jun 9. Protein Eng Des Sel. 2016. PMID: 27284085
Prediction and Reduction of the Aggregation of Monoclonal Antibodies.
van der Kant R, Karow-Zwick AR, Van Durme J, Blech M, Gallardo R, Seeliger D, Aßfalg K, Baatsen P, Compernolle G, Gils A, Studts JM, Schulz P, Garidel P, Schymkowitz J, Rousseau F. van der Kant R, et al. Among authors: van durme j. J Mol Biol. 2017 Apr 21;429(8):1244-1261. doi: 10.1016/j.jmb.2017.03.014. Epub 2017 Mar 18. J Mol Biol. 2017. PMID: 28322916 Free PMC article.
Hsp90 Mediates Membrane Deformation and Exosome Release.
Lauwers E, Wang YC, Gallardo R, Van der Kant R, Michiels E, Swerts J, Baatsen P, Zaiter SS, McAlpine SR, Gounko NV, Rousseau F, Schymkowitz J, Verstreken P. Lauwers E, et al. Among authors: van der kant r. Mol Cell. 2018 Sep 6;71(5):689-702.e9. doi: 10.1016/j.molcel.2018.07.016. Mol Cell. 2018. PMID: 30193096 Free article.
Thermodynamic and Evolutionary Coupling between the Native and Amyloid State of Globular Proteins.
Langenberg T, Gallardo R, van der Kant R, Louros N, Michiels E, Duran-Romaña R, Houben B, Cassio R, Wilkinson H, Garcia T, Ulens C, Van Durme J, Rousseau F, Schymkowitz J. Langenberg T, et al. Among authors: van der kant r, van durme j. Cell Rep. 2020 Apr 14;31(2):107512. doi: 10.1016/j.celrep.2020.03.076. Cell Rep. 2020. PMID: 32294448 Free PMC article.
Defective Sec61α1 underlies a novel cause of autosomal dominant severe congenital neutropenia.
Van Nieuwenhove E, Barber JS, Neumann J, Smeets E, Willemsen M, Pasciuto E, Prezzemolo T, Lagou V, Seldeslachts L, Malengier-Devlies B, Metzemaekers M, Haßdenteufel S, Kerstens A, van der Kant R, Rousseau F, Schymkowitz J, Di Marino D, Lang S, Zimmermann R, Schlenner S, Munck S, Proost P, Matthys P, Devalck C, Boeckx N, Claessens F, Wouters C, Humblet-Baron S, Meyts I, Liston A. Van Nieuwenhove E, et al. Among authors: van der kant r. J Allergy Clin Immunol. 2020 Nov;146(5):1180-1193. doi: 10.1016/j.jaci.2020.03.034. Epub 2020 Apr 20. J Allergy Clin Immunol. 2020. PMID: 32325141 Free PMC article.
47 results