Kleanthous C - Search Results

1

High-resolution mass spectrometry of small molecules bound to membrane proteins.

Gault J, Donlan JA, Liko I, Hopper JT, Gupta K, Housden NG, Struwe WB, Marty MT, Mize T, Bechara C, Zhu Y, Wu B, Kleanthous C, Belov M, Damoc E, Makarov A, Robinson CV. Gault J, et al. Among authors: kleanthous c. Nat Methods. 2016 Apr;13(4):333-6. doi: 10.1038/nmeth.3771. Epub 2016 Feb 22. Nat Methods. 2016. PMID: 26901650 Free PMC article.

2

Flexibility in the receptor-binding domain of the enzymatic colicin E9 is required for toxicity against Escherichia coli cells.

Penfold CN, Healy B, Housden NG, Boetzel R, Vankemmelbeke M, Moore GR, Kleanthous C, James R. Penfold CN, et al. Among authors: kleanthous c. J Bacteriol. 2004 Jul;186(14):4520-7. doi: 10.1128/JB.186.14.4520-4527.2004. J Bacteriol. 2004. PMID: 15231784 Free PMC article.

3

Cell entry mechanism of enzymatic bacterial colicins: porin recruitment and the thermodynamics of receptor binding.

Housden NG, Loftus SR, Moore GR, James R, Kleanthous C. Housden NG, et al. Among authors: kleanthous c. Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13849-54. doi: 10.1073/pnas.0503567102. Epub 2005 Sep 15. Proc Natl Acad Sci U S A. 2005. PMID: 16166265 Free PMC article.

4

Allosteric beta-propeller signalling in TolB and its manipulation by translocating colicins.

Bonsor DA, Hecht O, Vankemmelbeke M, Sharma A, Krachler AM, Housden NG, Lilly KJ, James R, Moore GR, Kleanthous C. Bonsor DA, et al. Among authors: kleanthous c. EMBO J. 2009 Sep 16;28(18):2846-57. doi: 10.1038/emboj.2009.224. Epub 2009 Aug 20. EMBO J. 2009. PMID: 19696740 Free PMC article.

5

Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF.

Housden NG, Wojdyla JA, Korczynska J, Grishkovskaya I, Kirkpatrick N, Brzozowski AM, Kleanthous C. Housden NG, et al. Among authors: kleanthous c. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21412-7. doi: 10.1073/pnas.1010780107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098297 Free PMC article.

6

Thermodynamic dissection of colicin interactions.

Housden NG, Kleanthous C. Housden NG, et al. Among authors: kleanthous c. Methods Enzymol. 2011;488:123-45. doi: 10.1016/B978-0-12-381268-1.00006-9. Methods Enzymol. 2011. PMID: 21195227 Review.

7

Kinetic basis for the competitive recruitment of TolB by the intrinsically disordered translocation domain of colicin E9.

Papadakos G, Housden NG, Lilly KJ, Kaminska R, Kleanthous C. Papadakos G, et al. Among authors: kleanthous c. J Mol Biol. 2012 May 18;418(5):269-80. doi: 10.1016/j.jmb.2012.01.039. Epub 2012 Jan 30. J Mol Biol. 2012. PMID: 22310049 Free article.

8

Colicin translocation across the Escherichia coli outer membrane.

Housden NG, Kleanthous C. Housden NG, et al. Among authors: kleanthous c. Biochem Soc Trans. 2012 Dec 1;40(6):1475-9. doi: 10.1042/BST20120255. Biochem Soc Trans. 2012. PMID: 23176501 Review.

9

A force-activated trip switch triggers rapid dissociation of a colicin from its immunity protein.

Farrance OE, Hann E, Kaminska R, Housden NG, Derrington SR, Kleanthous C, Radford SE, Brockwell DJ. Farrance OE, et al. Among authors: kleanthous c. PLoS Biol. 2013;11(2):e1001489. doi: 10.1371/journal.pbio.1001489. Epub 2013 Feb 19. PLoS Biol. 2013. PMID: 23431269 Free PMC article.

10

Intrinsically disordered protein threads through the bacterial outer-membrane porin OmpF.

Housden NG, Hopper JT, Lukoyanova N, Rodriguez-Larrea D, Wojdyla JA, Klein A, Kaminska R, Bayley H, Saibil HR, Robinson CV, Kleanthous C. Housden NG, et al. Among authors: kleanthous c. Science. 2013 Jun 28;340(6140):1570-4. doi: 10.1126/science.1237864. Science. 2013. PMID: 23812713 Free PMC article.

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