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New tools for studying microglia in the mouse and human CNS.
Bennett ML, Bennett FC, Liddelow SA, Ajami B, Zamanian JL, Fernhoff NB, Mulinyawe SB, Bohlen CJ, Adil A, Tucker A, Weissman IL, Chang EF, Li G, Grant GA, Hayden Gephart MG, Barres BA. Bennett ML, et al. Among authors: ajami b. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):E1738-46. doi: 10.1073/pnas.1525528113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884166 Free PMC article.
Microglia states and nomenclature: A field at its crossroads.
Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, Boddeke E, Brites D, Brône B, Brown GC, Butovsky O, Carson MJ, Castellano B, Colonna M, Cowley SA, Cunningham C, Davalos D, De Jager PL, de Strooper B, Denes A, Eggen BJL, Eyo U, Galea E, Garel S, Ginhoux F, Glass CK, Gokce O, Gomez-Nicola D, González B, Gordon S, Graeber MB, Greenhalgh AD, Gressens P, Greter M, Gutmann DH, Haass C, Heneka MT, Heppner FL, Hong S, Hume DA, Jung S, Kettenmann H, Kipnis J, Koyama R, Lemke G, Lynch M, Majewska A, Malcangio M, Malm T, Mancuso R, Masuda T, Matteoli M, McColl BW, Miron VE, Molofsky AV, Monje M, Mracsko E, Nadjar A, Neher JJ, Neniskyte U, Neumann H, Noda M, Peng B, Peri F, Perry VH, Popovich PG, Pridans C, Priller J, Prinz M, Ragozzino D, Ransohoff RM, Salter MW, Schaefer A, Schafer DP, Schwartz M, Simons M, Smith CJ, Streit WJ, Tay TL, Tsai LH, Verkhratsky A, von Bernhardi R, Wake H, Wittamer V, Wolf SA, Wu LJ, Wyss-Coray T. Paolicelli RC, et al. Among authors: ajami b. Neuron. 2022 Nov 2;110(21):3458-3483. doi: 10.1016/j.neuron.2022.10.020. Neuron. 2022. PMID: 36327895 Free PMC article. Review.
Elevated α5 integrin expression on myeloid cells in motor areas in amyotrophic lateral sclerosis is a therapeutic target.
Chiot A, Roemer SF, Ryner L, Bogachuk A, Emberley K, Brownell D, Jimenez GA, Leviten M, Woltjer R, Dickson DW, Steinman L, Ajami B. Chiot A, et al. Among authors: ajami b. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2306731120. doi: 10.1073/pnas.2306731120. Epub 2023 Jul 31. Proc Natl Acad Sci U S A. 2023. PMID: 37523555 Free PMC article.
Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.
Marabelle A, Kohrt H, Sagiv-Barfi I, Ajami B, Axtell RC, Zhou G, Rajapaksa R, Green MR, Torchia J, Brody J, Luong R, Rosenblum MD, Steinman L, Levitsky HI, Tse V, Levy R. Marabelle A, et al. Among authors: ajami b. J Clin Invest. 2013 Jun;123(6):2447-63. doi: 10.1172/JCI64859. J Clin Invest. 2013. PMID: 23728179 Free PMC article.
29 results