Stewart A - Search Results

1

Mutation of cancer driver MLL2 results in transcription stress and genome instability.

Kantidakis T, Saponaro M, Mitter R, Horswell S, Kranz A, Boeing S, Aygün O, Kelly GP, Matthews N, Stewart A, Stewart AF, Svejstrup JQ. Kantidakis T, et al. Among authors: stewart a, stewart af. Genes Dev. 2016 Feb 15;30(4):408-20. doi: 10.1101/gad.275453.115. Genes Dev. 2016. PMID: 26883360 Free PMC article.

2

Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development.

Glaser S, Schaft J, Lubitz S, Vintersten K, van der Hoeven F, Tufteland KR, Aasland R, Anastassiadis K, Ang SL, Stewart AF. Glaser S, et al. Among authors: stewart af. Development. 2006 Apr;133(8):1423-32. doi: 10.1242/dev.02302. Epub 2006 Mar 15. Development. 2006. PMID: 16540515

3

Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2.

Lubitz S, Glaser S, Schaft J, Stewart AF, Anastassiadis K. Lubitz S, et al. Among authors: stewart af. Mol Biol Cell. 2007 Jun;18(6):2356-66. doi: 10.1091/mbc.e06-11-1060. Epub 2007 Apr 11. Mol Biol Cell. 2007. PMID: 17429066 Free PMC article.

4

The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis.

Glaser S, Lubitz S, Loveland KL, Ohbo K, Robb L, Schwenk F, Seibler J, Roellig D, Kranz A, Anastassiadis K, Stewart AF. Glaser S, et al. Among authors: stewart af. Epigenetics Chromatin. 2009 Apr 6;2(1):5. doi: 10.1186/1756-8935-2-5. Epigenetics Chromatin. 2009. PMID: 19348672 Free PMC article.

5

An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase.

Kranz A, Fu J, Duerschke K, Weidlich S, Naumann R, Stewart AF, Anastassiadis K. Kranz A, et al. Among authors: stewart af. Genesis. 2010 Aug;48(8):512-20. doi: 10.1002/dvg.20641. Genesis. 2010. PMID: 20506501

6

A practical summary of site-specific recombination, conditional mutagenesis, and tamoxifen induction of CreERT2.

Anastassiadis K, Glaser S, Kranz A, Berhardt K, Stewart AF. Anastassiadis K, et al. Among authors: stewart af. Methods Enzymol. 2010;477:109-23. doi: 10.1016/S0076-6879(10)77007-5. Methods Enzymol. 2010. PMID: 20699139

7

Histone-methyltransferase MLL2 (KMT2B) is required for memory formation in mice.

Kerimoglu C, Agis-Balboa RC, Kranz A, Stilling R, Bahari-Javan S, Benito-Garagorri E, Halder R, Burkhardt S, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: stewart af. J Neurosci. 2013 Feb 20;33(8):3452-64. doi: 10.1523/JNEUROSCI.3356-12.2013. J Neurosci. 2013. PMID: 23426673 Free PMC article.

8

Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.

Denissov S, Hofemeister H, Marks H, Kranz A, Ciotta G, Singh S, Anastassiadis K, Stunnenberg HG, Stewart AF. Denissov S, et al. Among authors: stewart af. Development. 2014 Feb;141(3):526-37. doi: 10.1242/dev.102681. Epub 2014 Jan 14. Development. 2014. PMID: 24423662

9

The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation.

Bledau AS, Schmidt K, Neumann K, Hill U, Ciotta G, Gupta A, Torres DC, Fu J, Kranz A, Stewart AF, Anastassiadis K. Bledau AS, et al. Among authors: stewart af. Development. 2014 Mar;141(5):1022-35. doi: 10.1242/dev.098152. Development. 2014. PMID: 24550110

10

DNA annealing by Redβ is insufficient for homologous recombination and the additional requirements involve intra- and inter-molecular interactions.

Subramaniam S, Erler A, Fu J, Kranz A, Tang J, Gopalswamy M, Ramakrishnan S, Keller A, Grundmeier G, Müller D, Sattler M, Stewart AF. Subramaniam S, et al. Among authors: stewart af. Sci Rep. 2016 Oct 6;6:34525. doi: 10.1038/srep34525. Sci Rep. 2016. PMID: 27708411 Free PMC article.

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