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In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
Benvenuto M, Masuelli L, De Smaele E, Fantini M, Mattera R, Cucchi D, Bonanno E, Di Stefano E, Frajese GV, Orlandi A, Screpanti I, Gulino A, Modesti A, Bei R. Benvenuto M, et al. Among authors: modesti a. Oncotarget. 2016 Feb 23;7(8):9250-70. doi: 10.18632/oncotarget.7062. Oncotarget. 2016. PMID: 26843616 Free PMC article.
Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas.
Masuelli L, Di Stefano E, Fantini M, Mattera R, Benvenuto M, Marzocchella L, Sacchetti P, Focaccetti C, Bernardini R, Tresoldi I, Izzi V, Mattei M, Frajese GV, Lista F, Modesti A, Bei R. Masuelli L, et al. Among authors: modesti a. Oncotarget. 2014 Nov 15;5(21):10745-62. doi: 10.18632/oncotarget.2534. Oncotarget. 2014. PMID: 25296980 Free PMC article.
(±)-Gossypol induces apoptosis and autophagy in head and neck carcinoma cell lines and inhibits the growth of transplanted salivary gland cancer cells in BALB/c mice.
Benvenuto M, Mattera R, Masuelli L, Taffera G, Andracchio O, Tresoldi I, Lido P, Giganti MG, Godos J, Modesti A, Bei R. Benvenuto M, et al. Among authors: modesti a. Int J Food Sci Nutr. 2017 May;68(3):298-312. doi: 10.1080/09637486.2016.1236077. Epub 2016 Sep 27. Int J Food Sci Nutr. 2017. PMID: 27670669
Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line.
Masuelli L, Benvenuto M, Di Stefano E, Mattera R, Fantini M, De Feudis G, De Smaele E, Tresoldi I, Giganti MG, Modesti A, Bei R. Masuelli L, et al. Among authors: modesti a. Oncotarget. 2017 May 23;8(21):34405-34422. doi: 10.18632/oncotarget.14907. Oncotarget. 2017. PMID: 28159921 Free PMC article.
Combined treatment with inhibitors of ErbB Receptors and Hh signaling pathways is more effective than single treatment in reducing the growth of malignant mesothelioma both in vitro and in vivo.
Bei R, Benvenuto M, Focaccetti C, Fazi S, Moretti M, Nardozi D, Angiolini V, Ciuffa S, Cifaldi L, Carrano R, Palumbo C, Miele MT, Bei R, Barillari G, Manzari V, De Smaele E, Modesti A, Masuelli L. Bei R, et al. Among authors: modesti a. J Transl Med. 2022 Jun 25;20(1):286. doi: 10.1186/s12967-022-03490-9. J Transl Med. 2022. PMID: 35752861 Free PMC article.
Local delivery of recombinant vaccinia virus encoding for neu counteracts growth of mammary tumors more efficiently than systemic delivery in neu transgenic mice.
Masuelli L, Marzocchella L, Focaccetti C, Lista F, Nardi A, Scardino A, Mattei M, Turriziani M, Modesti M, Forni G, Schlom J, Modesti A, Bei R. Masuelli L, et al. Among authors: modesti m, modesti a. Cancer Immunol Immunother. 2010 Aug;59(8):1247-58. doi: 10.1007/s00262-010-0850-0. Epub 2010 Apr 4. Cancer Immunol Immunother. 2010. PMID: 20364378 Free PMC article.
Spontaneous immunogenicity of ribosomal P0 protein in patients with benign and malignant breast lesions and delay of mammary tumor growth in P0-vaccinated mice.
Marzocchella L, Sini V, Buonomo O, Orlandi A, Masuelli L, Bonanno E, Lista F, Turriziani M, Manzari V, Roselli M, Modesti A, Bei R. Marzocchella L, et al. Among authors: modesti a. Cancer Sci. 2011 Mar;102(3):509-15. doi: 10.1111/j.1349-7006.2010.01814.x. Epub 2010 Dec 22. Cancer Sci. 2011. PMID: 21175994 Free article.
328 results