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S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure.
Stathopoulou K, Wittig I, Heidler J, Piasecki A, Richter F, Diering S, van der Velden J, Buck F, Donzelli S, Schröder E, Wijnker PJ, Voigt N, Dobrev D, Sadayappan S, Eschenhagen T, Carrier L, Eaton P, Cuello F. Stathopoulou K, et al. Among authors: piasecki a. FASEB J. 2016 May;30(5):1849-64. doi: 10.1096/fj.201500048. Epub 2016 Feb 2. FASEB J. 2016. PMID: 26839380 Free PMC article.
We used redox proteomics, to identify constitutive and disease-specific S-glutathiolation sites in cMyBP-C in donor and patient samples, respectively. Among those, a cysteine cluster in the vicinity of the regulatory phosphorylation sites within the myosin S2 interaction d …
We used redox proteomics, to identify constitutive and disease-specific S-glutathiolation sites in cMyBP-C in donor and patient samples, res …
Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation.
Schaefer A, Schneeberger Y, Schulz S, Krasemann S, Werner T, Piasecki A, Höppner G, Müller C, Morhenn K, Lorenz K, Wieczorek D, Schwoerer AP, Eschenhagen T, Ehmke H, Reichenspurner H, Stenzig J, Cuello F. Schaefer A, et al. Among authors: piasecki a. Sci Rep. 2019 Apr 5;9(1):5710. doi: 10.1038/s41598-019-42263-1. Sci Rep. 2019. PMID: 30952943 Free PMC article.
Receptor-independent modulation of cAMP-dependent protein kinase and protein phosphatase signaling in cardiac myocytes by oxidizing agents.
Diering S, Stathopoulou K, Goetz M, Rathjens L, Harder S, Piasecki A, Raabe J, Schulz S, Brandt M, Pflaumenbaum J, Fuchs U, Donzelli S, Sadayappan S, Nikolaev VO, Flenner F, Ehler E, Cuello F. Diering S, et al. Among authors: piasecki a. J Biol Chem. 2020 Nov 6;295(45):15342-15365. doi: 10.1074/jbc.RA120.014467. Epub 2020 Aug 31. J Biol Chem. 2020. PMID: 32868295 Free PMC article.
Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue.
Rhoden A, Friedrich FW, Brandt T, Raabe J, Schweizer M, Meisterknecht J, Wittig I, Ulmer BM, Klampe B, Uebeler J, Piasecki A, Lorenz K, Eschenhagen T, Hansen A, Cuello F. Rhoden A, et al. Among authors: piasecki a. Redox Biol. 2021 May;41:101951. doi: 10.1016/j.redox.2021.101951. Epub 2021 Mar 31. Redox Biol. 2021. PMID: 33831709 Free PMC article.
Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation.
Cuello F, Knaust AE, Saleem U, Loos M, Raabe J, Mosqueira D, Laufer S, Schweizer M, van der Kraak P, Flenner F, Ulmer BM, Braren I, Yin X, Theofilatos K, Ruiz-Orera J, Patone G, Klampe B, Schulze T, Piasecki A, Pinto Y, Vink A, Hübner N, Harding S, Mayr M, Denning C, Eschenhagen T, Hansen A. Cuello F, et al. Among authors: piasecki a. EMBO Mol Med. 2021 Jun 7;13(6):e13074. doi: 10.15252/emmm.202013074. Epub 2021 May 16. EMBO Mol Med. 2021. PMID: 33998164 Free PMC article.
CMYA5 is a novel interaction partner of FHL2 in cardiac myocytes.
Stathopoulou K, Schnittger J, Raabe J, Fleischer F, Mangels N, Piasecki A, Findlay J, Hartmann K, Krasemann S, Schlossarek S, Uebeler J, Wixler V, Blake DJ, Baillie GS, Carrier L, Ehler E, Cuello F. Stathopoulou K, et al. Among authors: piasecki a. FEBS J. 2022 Aug;289(15):4622-4645. doi: 10.1111/febs.16402. Epub 2022 Feb 27. FEBS J. 2022. PMID: 35176204 Free article.
PITX2 deficiency leads to atrial mitochondrial dysfunction.
Reyat JS, Sommerfeld LC, O'Reilly M, Cardoso VR, Thiemann E, Khan AO, O'Shea C, Harder S, Müller C, Barlow J, Stapley RJ, Chua W, Kabir SN, Grech O, Hummel O, Hübner N, Kääb S, Mont L, Hatem SN, Winters J, Zeemering S, Morgan NV, Rayes J, Gehmlich K, Stoll M, Brand T, Schweizer M, Piasecki A, Schotten U, Gkoutos GV, Lorenz K, Cuello F, Kirchhof P, Fabritz L. Reyat JS, et al. Among authors: piasecki a. Cardiovasc Res. 2024 Aug 12:cvae169. doi: 10.1093/cvr/cvae169. Online ahead of print. Cardiovasc Res. 2024. PMID: 39129206
122 results