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Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans.
Sevastianova K, Kotronen A, Gastaldelli A, Perttilä J, Hakkarainen A, Lundbom J, Suojanen L, Orho-Melander M, Lundbom N, Ferrannini E, Rissanen A, Olkkonen VM, Yki-Järvinen H. Sevastianova K, et al. Among authors: gastaldelli a. Am J Clin Nutr. 2011 Jul;94(1):104-11. doi: 10.3945/ajcn.111.012369. Epub 2011 Apr 27. Am J Clin Nutr. 2011. PMID: 21525193 Free article. Clinical Trial.
Pathophysiology of Non Alcoholic Fatty Liver Disease.
Petta S, Gastaldelli A, Rebelos E, Bugianesi E, Messa P, Miele L, Svegliati-Baroni G, Valenti L, Bonino F. Petta S, et al. Among authors: gastaldelli a. Int J Mol Sci. 2016 Dec 11;17(12):2082. doi: 10.3390/ijms17122082. Int J Mol Sci. 2016. PMID: 27973438 Free PMC article. Review.
Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study.
Isokuortti E, Zhou Y, Peltonen M, Bugianesi E, Clement K, Bonnefont-Rousselot D, Lacorte JM, Gastaldelli A, Schuppan D, Schattenberg JM, Hakkarainen A, Lundbom N, Jousilahti P, Männistö S, Keinänen-Kiukaanniemi S, Saltevo J, Anstee QM, Yki-Järvinen H. Isokuortti E, et al. Among authors: gastaldelli a. Diabetologia. 2017 Oct;60(10):1873-1882. doi: 10.1007/s00125-017-4340-1. Epub 2017 Jun 29. Diabetologia. 2017. PMID: 28660493
Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars.
Luukkonen PK, Sädevirta S, Zhou Y, Kayser B, Ali A, Ahonen L, Lallukka S, Pelloux V, Gaggini M, Jian C, Hakkarainen A, Lundbom N, Gylling H, Salonen A, Orešič M, Hyötyläinen T, Orho-Melander M, Rissanen A, Gastaldelli A, Clément K, Hodson L, Yki-Järvinen H. Luukkonen PK, et al. Among authors: gastaldelli a. Diabetes Care. 2018 Aug;41(8):1732-1739. doi: 10.2337/dc18-0071. Epub 2018 May 29. Diabetes Care. 2018. PMID: 29844096 Free PMC article. Clinical Trial.
Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease.
Luukkonen PK, Tukiainen T, Juuti A, Sammalkorpi H, Haridas PAN, Niemelä O, Arola J, Orho-Melander M, Hakkarainen A, Kovanen PT, Dwivedi O, Groop L, Hodson L, Gastaldelli A, Hyötyläinen T, Orešič M, Yki-Järvinen H. Luukkonen PK, et al. Among authors: gastaldelli a. JCI Insight. 2020 Mar 12;5(5):e132158. doi: 10.1172/jci.insight.132158. JCI Insight. 2020. PMID: 32161197 Free PMC article.
The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue.
Qadri S, Lallukka-Brück S, Luukkonen PK, Zhou Y, Gastaldelli A, Orho-Melander M, Sammalkorpi H, Juuti A, Penttilä AK, Perttilä J, Hakkarainen A, Lehtimäki TE, Orešič M, Hyötyläinen T, Hodson L, Olkkonen VM, Yki-Järvinen H. Qadri S, et al. Among authors: gastaldelli a. Liver Int. 2020 Sep;40(9):2128-2138. doi: 10.1111/liv.14507. Epub 2020 May 18. Liver Int. 2020. PMID: 32386450
369 results