Jacobson KA - Search Results

1

Rigid Adenine Nucleoside Derivatives as Novel Modulators of the Human Sodium Symporters for Dopamine and Norepinephrine.

Janowsky A, Tosh DK, Eshleman AJ, Jacobson KA. Janowsky A, et al. Among authors: jacobson ka. J Pharmacol Exp Ther. 2016 Apr;357(1):24-35. doi: 10.1124/jpet.115.229666. Epub 2016 Jan 26. J Pharmacol Exp Ther. 2016. PMID: 26813929 Free PMC article.

2

Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism.

Nikodijević O, Sarges R, Daly JW, Jacobson KA. Nikodijević O, et al. Among authors: jacobson ka. J Pharmacol Exp Ther. 1991 Oct;259(1):286-94. J Pharmacol Exp Ther. 1991. PMID: 1920121 Free PMC article.

3

Adenosine receptor prodrugs: towards kidney-selective dialkylxanthines.

Barone S, Churchill PC, Jacobson KA. Barone S, et al. Among authors: jacobson ka. J Pharmacol Exp Ther. 1989 Jul;250(1):79-85. J Pharmacol Exp Ther. 1989. PMID: 2746513 Free PMC article.

4

Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists.

van Rhee AM, Siddiqi SM, Melman N, Shi D, Padgett WL, Daly JW, Jacobson KA. van Rhee AM, et al. Among authors: jacobson ka. J Med Chem. 1996 Jan 19;39(2):398-406. doi: 10.1021/jm9504823. J Med Chem. 1996. PMID: 8558508 Free PMC article.

5

Synthesis using ring closure metathesis and effect on nucleoside transport of a (N)-methanocarba S-(4-nitrobenzyl)thioinosine derivative.

Lee K, Cass C, Jacobson KA. Lee K, et al. Among authors: jacobson ka. Org Lett. 2001 Feb 22;3(4):597-9. doi: 10.1021/ol006999c. Org Lett. 2001. PMID: 11178834 Free PMC article.

6

Allosteric modulation of A(3) adenosine receptors by a series of 3-(2-pyridinyl)isoquinoline derivatives.

Gao ZG, Van Muijlwijk-Koezen JE, Chen A, Müller CE, Ijzerman AP, Jacobson KA. Gao ZG, et al. Among authors: jacobson ka. Mol Pharmacol. 2001 Nov;60(5):1057-63. Mol Pharmacol. 2001. PMID: 11641434 Free PMC article.

7

Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives.

Gao ZG, Kim SG, Soltysiak KA, Melman N, IJzerman AP, Jacobson KA. Gao ZG, et al. Among authors: jacobson ka. Mol Pharmacol. 2002 Jul;62(1):81-9. doi: 10.1124/mol.62.1.81. Mol Pharmacol. 2002. PMID: 12065758 Free PMC article.

8

N6-Substituted adenosine derivatives: selectivity, efficacy, and species differences at A3 adenosine receptors.

Gao ZG, Blaustein JB, Gross AS, Melman N, Jacobson KA. Gao ZG, et al. Among authors: jacobson ka. Biochem Pharmacol. 2003 May 15;65(10):1675-84. doi: 10.1016/s0006-2952(03)00153-9. Biochem Pharmacol. 2003. PMID: 12754103 Free PMC article.

9

Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety.

Gao ZG, Jeong LS, Moon HR, Kim HO, Choi WJ, Shin DH, Elhalem E, Comin MJ, Melman N, Mamedova L, Gross AS, Rodriguez JB, Jacobson KA. Gao ZG, et al. Among authors: jacobson ka. Biochem Pharmacol. 2004 Mar 1;67(5):893-901. doi: 10.1016/j.bcp.2003.10.006. Biochem Pharmacol. 2004. PMID: 15104242 Free PMC article.

10

2-Substituted adenosine derivatives: affinity and efficacy at four subtypes of human adenosine receptors.

Gao ZG, Mamedova LK, Chen P, Jacobson KA. Gao ZG, et al. Among authors: jacobson ka. Biochem Pharmacol. 2004 Nov 15;68(10):1985-93. doi: 10.1016/j.bcp.2004.06.011. Biochem Pharmacol. 2004. PMID: 15476669 Free PMC article.

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