Guchelaar HJ - Search Results

1

Sunitinib-induced hypertension in CYP3A4 rs4646437 A-allele carriers with metastatic renal cell carcinoma.

Diekstra MH, Belaustegui A, Swen JJ, Boven E, Castellano D, Gelderblom H, Mathijssen RH, García-Donas J, Rodríguez-Antona C, Rini BI, Guchelaar HJ. Diekstra MH, et al. Among authors: guchelaar hj. Pharmacogenomics J. 2017 Jan;17(1):42-46. doi: 10.1038/tpj.2015.100. Epub 2016 Jan 26. Pharmacogenomics J. 2017. PMID: 26810136

2

Polymorphisms in endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension.

Eechoute K, van der Veldt AA, Oosting S, Kappers MH, Wessels JA, Gelderblom H, Guchelaar HJ, Reyners AK, van Herpen CM, Haanen JB, Mathijssen RH, Boven E. Eechoute K, et al. Among authors: guchelaar hj. Clin Pharmacol Ther. 2012 Oct;92(4):503-10. doi: 10.1038/clpt.2012.136. Epub 2012 Sep 5. Clin Pharmacol Ther. 2012. PMID: 22948895

3

Pharmacogenetics in the cancer clinic: from candidate gene studies to next-generation sequencing.

Guchelaar HJ, Gelderblom H, van der Straaten T, Schellens JH, Swen JJ. Guchelaar HJ, et al. Clin Pharmacol Ther. 2014 Apr;95(4):383-5. doi: 10.1038/clpt.2014.13. Epub 2014 Jan 21. Clin Pharmacol Ther. 2014. PMID: 24448475

4

Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy.

Kweekel DM, Gelderblom H, Guchelaar HJ. Kweekel DM, et al. Among authors: guchelaar hj. Cancer Treat Rev. 2005 Apr;31(2):90-105. doi: 10.1016/j.ctrv.2004.12.006. Cancer Treat Rev. 2005. PMID: 15847979 Review.

5

Capecitabine-Induced Severe Toxicity Secondary to DPD Deficiency and Successful Treatment with Low Dose 5-Fluorouracil.

Lunenburg C, Swen JJ, Guchelaar HJ, Gelderblom H. Lunenburg C, et al. Among authors: guchelaar hj. J Gastrointest Cancer. 2017 Mar;48(1):117-118. doi: 10.1007/s12029-016-9908-3. J Gastrointest Cancer. 2017. PMID: 28025815 No abstract available.

6

Evaluation of predictive tests for screening for dihydropyrimidine dehydrogenase deficiency.

van Staveren MC, Guchelaar HJ, van Kuilenburg AB, Gelderblom H, Maring JG. van Staveren MC, et al. Among authors: guchelaar hj. Pharmacogenomics J. 2013 Oct;13(5):389-95. doi: 10.1038/tpj.2013.25. Epub 2013 Jul 16. Pharmacogenomics J. 2013. PMID: 23856855 Review.

7

Pharmacogenetic interaction analysis for the efficacy of systemic treatment in metastatic colorectal cancer.

Pander J, Wessels JAM, Gelderblom H, van der Straaten T, Punt CJA, Guchelaar HJ. Pander J, et al. Among authors: guchelaar hj. Ann Oncol. 2011 May;22(5):1147-1153. doi: 10.1093/annonc/mdq572. Epub 2010 Nov 3. Ann Oncol. 2011. PMID: 21048041 Free article. Clinical Trial.

8

The role of pharmacogenetics in drug disposition and response of oral glucose-lowering drugs.

van Leeuwen N, Swen JJ, Guchelaar HJ, 't Hart LM. van Leeuwen N, et al. Among authors: guchelaar hj. Clin Pharmacokinet. 2013 Oct;52(10):833-54. doi: 10.1007/s40262-013-0076-3. Clin Pharmacokinet. 2013. PMID: 23719679 Review.

9

Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.

Kweekel DM, Antonini NF, Nortier JW, Punt CJ, Gelderblom H, Guchelaar HJ. Kweekel DM, et al. Among authors: guchelaar hj. Br J Cancer. 2009 Jul 21;101(2):357-62. doi: 10.1038/sj.bjc.6605134. Epub 2009 Jun 16. Br J Cancer. 2009. PMID: 19536092 Free PMC article. Clinical Trial.

10

Myelosuppression by sunitinib is flt-3 genotype dependent.

van Erp NP, Mathijssen RH, van der Veldt AA, Haanen JB, Reyners AK, Eechoute K, Boven E, Wessels JA, Guchelaar HJ, Gelderblom H. van Erp NP, et al. Among authors: guchelaar hj. Br J Cancer. 2010 Aug 24;103(5):757-8. doi: 10.1038/sj.bjc.6605813. Epub 2010 Aug 3. Br J Cancer. 2010. PMID: 20683446 Free PMC article. No abstract available.

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