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An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.
Qi W, Zhao K, Gu J, Huang Y, Wang Y, Zhang H, Zhang M, Zhang J, Yu Z, Li L, Teng L, Chuai S, Zhang C, Zhao M, Chan H, Chen Z, Fang D, Fei Q, Feng L, Feng L, Gao Y, Ge H, Ge X, Li G, Lingel A, Lin Y, Liu Y, Luo F, Shi M, Wang L, Wang Z, Yu Y, Zeng J, Zeng C, Zhang L, Zhang Q, Zhou S, Oyang C, Atadja P, Li E. Qi W, et al. Among authors: gao y. Nat Chem Biol. 2017 Apr;13(4):381-388. doi: 10.1038/nchembio.2304. Epub 2017 Jan 30. Nat Chem Biol. 2017. PMID: 28135235
Special Enrichment Strategies Greatly Increase the Efficiency of Missing Proteins Identification from Regular Proteome Samples.
Su N, Zhang C, Zhang Y, Wang Z, Fan F, Zhao M, Wu F, Gao Y, Li Y, Chen L, Tian M, Zhang T, Wen B, Sensang N, Xiong Z, Wu S, Liu S, Yang P, Zhen B, Zhu Y, He F, Xu P. Su N, et al. Among authors: gao y. J Proteome Res. 2015 Sep 4;14(9):3680-92. doi: 10.1021/acs.jproteome.5b00481. Epub 2015 Jul 15. J Proteome Res. 2015. PMID: 26144840
Tissue-Based Proteogenomics Reveals that Human Testis Endows Plentiful Missing Proteins.
Zhang Y, Li Q, Wu F, Zhou R, Qi Y, Su N, Chen L, Xu S, Jiang T, Zhang C, Cheng G, Chen X, Kong D, Wang Y, Zhang T, Zi J, Wei W, Gao Y, Zhen B, Xiong Z, Wu S, Yang P, Wang Q, Wen B, He F, Xu P, Liu S. Zhang Y, et al. Among authors: gao y. J Proteome Res. 2015 Sep 4;14(9):3583-94. doi: 10.1021/acs.jproteome.5b00435. J Proteome Res. 2015. PMID: 26282447
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