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Page 1
MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53.
Wienken M, Dickmanns A, Nemajerova A, Kramer D, Najafova Z, Weiss M, Karpiuk O, Kassem M, Zhang Y, Lozano G, Johnsen SA, Moll UM, Zhang X, Dobbelstein M. Wienken M, et al. Among authors: karpiuk o. Mol Cell. 2016 Jan 7;61(1):68-83. doi: 10.1016/j.molcel.2015.12.008. Epub 2015 Dec 31. Mol Cell. 2016. PMID: 26748827 Free PMC article.
SIRT2 directs the replication stress response through CDK9 deacetylation.
Zhang H, Park SH, Pantazides BG, Karpiuk O, Warren MD, Hardy CW, Duong DM, Park SJ, Kim HS, Vassilopoulos A, Seyfried NT, Johnsen SA, Gius D, Yu DS. Zhang H, et al. Among authors: karpiuk o. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13546-51. doi: 10.1073/pnas.1301463110. Epub 2013 Jul 29. Proc Natl Acad Sci U S A. 2013. PMID: 23898190 Free PMC article.
Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival.
Dietachmayr M, Rathakrishnan A, Karpiuk O, von Zweydorf F, Engleitner T, Fernández-Sáiz V, Schenk P, Ueffing M, Rad R, Eilers M, Gloeckner CJ, Clemm von Hohenberg K, Bassermann F. Dietachmayr M, et al. Among authors: karpiuk o. Nat Commun. 2020 Mar 9;11(1):1268. doi: 10.1038/s41467-020-15059-5. Nat Commun. 2020. PMID: 32152317 Free PMC article.
The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
Paulmann C, Spallek R, Karpiuk O, Heider M, Schäffer I, Zecha J, Klaeger S, Walzik M, Öllinger R, Engleitner T, Wirth M, Keller U, Krönke J, Rudelius M, Kossatz S, Rad R, Kuster B, Bassermann F. Paulmann C, et al. Among authors: karpiuk o. EMBO J. 2022 Oct 17;41(20):e110871. doi: 10.15252/embj.2022110871. Epub 2022 Sep 5. EMBO J. 2022. PMID: 36059274 Free PMC article.
MOF maintains transcriptional programs regulating cellular stress response.
Sheikh BN, Bechtel-Walz W, Lucci J, Karpiuk O, Hild I, Hartleben B, Vornweg J, Helmstädter M, Sahyoun AH, Bhardwaj V, Stehle T, Diehl S, Kretz O, Voss AK, Thomas T, Manke T, Huber TB, Akhtar A. Sheikh BN, et al. Among authors: karpiuk o. Oncogene. 2016 May;35(21):2698-710. doi: 10.1038/onc.2015.335. Epub 2015 Sep 21. Oncogene. 2016. PMID: 26387537 Free PMC article.