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Using observational data to emulate a randomized trial of dynamic treatment-switching strategies: an application to antiretroviral therapy.
Cain LE, Saag MS, Petersen M, May MT, Ingle SM, Logan R, Robins JM, Abgrall S, Shepherd BE, Deeks SG, John Gill M, Touloumi G, Vourli G, Dabis F, Vandenhende MA, Reiss P, van Sighem A, Samji H, Hogg RS, Rybniker J, Sabin CA, Jose S, Del Amo J, Moreno S, Rodríguez B, Cozzi-Lepri A, Boswell SL, Stephan C, Pérez-Hoyos S, Jarrin I, Guest JL, D'Arminio Monforte A, Antinori A, Moore R, Campbell CN, Casabona J, Meyer L, Seng R, Phillips AN, Bucher HC, Egger M, Mugavero MJ, Haubrich R, Geng EH, Olson A, Eron JJ, Napravnik S, Kitahata MM, Van Rompaey SE, Teira R, Justice AC, Tate JP, Costagliola D, Sterne JA, Hernán MA; Antiretroviral Therapy Cohort Collaboration, the Centers for AIDS Research Network of Integrated Clinical Systems, and the HIV-CAUSAL Collaboration. Cain LE, et al. Among authors: van sighem a, van rompaey se. Int J Epidemiol. 2016 Dec 1;45(6):2038-2049. doi: 10.1093/ije/dyv295. Int J Epidemiol. 2016. PMID: 26721599 Free PMC article.
CD4 cell counts of 800 cells/mm3 or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm3 or greater.
Gras L, Kesselring AM, Griffin JT, van Sighem AI, Fraser C, Ghani AC, Miedema F, Reiss P, Lange JM, de Wolf F; ATHENA, Netherlands National Observational Cohort Study. Gras L, et al. Among authors: van sighem ai. J Acquir Immune Defic Syndr. 2007 Jun 1;45(2):183-92. doi: 10.1097/QAI.0b013e31804d685b. J Acquir Immune Defic Syndr. 2007. PMID: 17414934
Combination antiretroviral therapy failure and HIV super-infection.
Bezemer D, van Sighem A, de Wolf F, Cornelissen M, van der Kuyl AC, Jurriaans S, van der Hoek L, Prins M, Coutinho RA, Lukashov VV. Bezemer D, et al. Among authors: van der kuyl ac, van sighem a, van der hoek l. AIDS. 2008 Jan 11;22(2):309-11. doi: 10.1097/QAD.0b013e3282f37489. AIDS. 2008. PMID: 18097235
Reemergence of the HIV epidemic among men who have sex with men in North America, Western Europe, and Australia, 1996-2005.
Sullivan PS, Hamouda O, Delpech V, Geduld JE, Prejean J, Semaille C, Kaldor J, Folch C, Op de Coul E, Marcus U, Hughes G, Archibald CP, Cazein F, McDonald A, Casabona J, van Sighem A, Fenton KA; Annecy MSM Epidemiology Study Group. Sullivan PS, et al. Among authors: van sighem a. Ann Epidemiol. 2009 Jun;19(6):423-31. doi: 10.1016/j.annepidem.2009.03.004. Ann Epidemiol. 2009. PMID: 19460672
The effect of combined antiretroviral therapy on the overall mortality of HIV-infected individuals.
HIV-CAUSAL Collaboration; Ray M, Logan R, Sterne JA, Hernández-Díaz S, Robins JM, Sabin C, Bansi L, van Sighem A, de Wolf F, Costagliola D, Lanoy E, Bucher HC, von Wyl V, Esteve A, Casbona J, del Amo J, Moreno S, Justice A, Goulet J, Lodi S, Phillips A, Seng R, Meyer L, Pérez-Hoyos S, García de Olalla P, Hernán MA. HIV-CAUSAL Collaboration, et al. Among authors: van sighem a. AIDS. 2010 Jan 2;24(1):123-37. doi: 10.1097/QAD.0b013e3283324283. AIDS. 2010. PMID: 19770621 Free PMC article.
175 results