Spreafico R - Search Results

1

Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei.

Langousis G, Shimogawa MM, Saada EA, Vashisht AA, Spreafico R, Nager AR, Barshop WD, Nachury MV, Wohlschlegel JA, Hill KL. Langousis G, et al. Among authors: spreafico r. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):632-7. doi: 10.1073/pnas.1518079113. Epub 2015 Dec 31. Proc Natl Acad Sci U S A. 2016. PMID: 26721397 Free PMC article.

2

Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor.

Mognol GP, González-Avalos E, Ghosh S, Spreafico R, Gudlur A, Rao A, Damoiseaux R, Hogan PG. Mognol GP, et al. Among authors: spreafico r. Proc Natl Acad Sci U S A. 2019 May 14;116(20):9959-9968. doi: 10.1073/pnas.1820604116. Epub 2019 Apr 24. Proc Natl Acad Sci U S A. 2019. PMID: 31019078 Free PMC article.

3

Epipolymorphisms associated with the clinical outcome of autoimmune arthritis affect CD4+ T cell activation pathways.

Spreafico R, Rossetti M, Whitaker JW, Wang W, Lovell DJ, Albani S. Spreafico R, et al. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):13845-13850. doi: 10.1073/pnas.1524056113. Epub 2016 Nov 14. Proc Natl Acad Sci U S A. 2016. PMID: 27849614 Free PMC article.

4

Transfer transcriptomic signatures for infectious diseases.

di Iulio J, Bartha I, Spreafico R, Virgin HW, Telenti A. di Iulio J, et al. Among authors: spreafico r. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2022486118. doi: 10.1073/pnas.2022486118. Proc Natl Acad Sci U S A. 2021. PMID: 34031243 Free PMC article.

5

Exhaustion-associated regulatory regions in CD8⁺ tumor-infiltrating T cells.

Mognol GP, Spreafico R, Wong V, Scott-Browne JP, Togher S, Hoffmann A, Hogan PG, Rao A, Trifari S. Mognol GP, et al. Among authors: spreafico r. Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):E2776-E2785. doi: 10.1073/pnas.1620498114. Epub 2017 Mar 10. Proc Natl Acad Sci U S A. 2017. PMID: 28283662 Free PMC article.

6

Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense.

Scumpia PO, Botten GA, Norman JS, Kelly-Scumpia KM, Spreafico R, Ruccia AR, Purbey PK, Thomas BJ, Modlin RL, Smale ST. Scumpia PO, et al. Among authors: spreafico r. PLoS Pathog. 2017 Jul 13;13(7):e1006496. doi: 10.1371/journal.ppat.1006496. eCollection 2017 Jul. PLoS Pathog. 2017. PMID: 28704551 Free PMC article.

7

PGRMC2 is an intracellular haem chaperone critical for adipocyte function.

Galmozzi A, Kok BP, Kim AS, Montenegro-Burke JR, Lee JY, Spreafico R, Mosure S, Albert V, Cintron-Colon R, Godio C, Webb WR, Conti B, Solt LA, Kojetin D, Parker CG, Peluso JJ, Pru JK, Siuzdak G, Cravatt BF, Saez E. Galmozzi A, et al. Among authors: spreafico r. Nature. 2019 Dec;576(7785):138-142. doi: 10.1038/s41586-019-1774-2. Epub 2019 Nov 20. Nature. 2019. PMID: 31748741 Free PMC article.

8

Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors.

Correa RG, Khan PM, Askari N, Zhai D, Gerlic M, Brown B, Magnuson G, Spreafico R, Albani S, Sergienko E, Diaz PW, Roth GP, Reed JC. Correa RG, et al. Among authors: spreafico r. Chem Biol. 2011 Jul 29;18(7):825-32. doi: 10.1016/j.chembiol.2011.06.009. Chem Biol. 2011. PMID: 21802003 Free PMC article.

9

Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: a possible mechanism for therapeutic modulation of T cells.

van Loosdregt J, Spreafico R, Rossetti M, Prakken BJ, Lotz M, Albani S. van Loosdregt J, et al. Among authors: spreafico r. J Allergy Clin Immunol. 2013 May;131(5):1443-6.e1. doi: 10.1016/j.jaci.2013.02.026. Epub 2013 Mar 28. J Allergy Clin Immunol. 2013. PMID: 23541328 Free PMC article.

10

Human CD4+CD3- innate-like T cells provide a source of TNF and lymphotoxin-αβ and are elevated in rheumatoid arthritis.

Bekiaris V, Šedy JR, Rossetti M, Spreafico R, Sharma S, Rhode-Kurnow A, Ware BC, Huang N, Macauley MG, Norris PS, Albani S, Ware CF. Bekiaris V, et al. Among authors: spreafico r. J Immunol. 2013 Nov 1;191(9):4611-8. doi: 10.4049/jimmunol.1301672. Epub 2013 Sep 27. J Immunol. 2013. PMID: 24078690 Free PMC article.

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