Thummel KE - Search Results

1

Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism.

Tracy TS, Chaudhry AS, Prasad B, Thummel KE, Schuetz EG, Zhong XB, Tien YC, Jeong H, Pan X, Shireman LM, Tay-Sontheimer J, Lin YS. Tracy TS, et al. Among authors: thummel ke. Drug Metab Dispos. 2016 Mar;44(3):343-51. doi: 10.1124/dmd.115.067900. Epub 2015 Dec 17. Drug Metab Dispos. 2016. PMID: 26681736 Free PMC article. Review.

2

Inhibition and activation of acetaminophen reactive metabolite formation by caffeine. Roles of cytochromes P-450IA1 and IIIA2.

Lee CA, Thummel KE, Kalhorn TF, Nelson SD, Slattery JT. Lee CA, et al. Among authors: thummel ke. Drug Metab Dispos. 1991 Mar-Apr;19(2):348-53. Drug Metab Dispos. 1991. PMID: 1676635

3

Activation of acetaminophen-reactive metabolite formation by methylxanthines and known cytochrome P-450 activators.

Lee CA, Thummel KE, Kalhorn TF, Nelson SD, Slattery JT. Lee CA, et al. Among authors: thummel ke. Drug Metab Dispos. 1991 Sep-Oct;19(5):966-71. Drug Metab Dispos. 1991. PMID: 1686244

4

Catalytic role of cytochrome P4503A4 in multiple pathways of alfentanil metabolism.

Labroo RB, Thummel KE, Kunze KL, Podoll T, Trager WF, Kharasch ED. Labroo RB, et al. Among authors: thummel ke. Drug Metab Dispos. 1995 Apr;23(4):490-6. Drug Metab Dispos. 1995. PMID: 7600917

5

Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation.

Thummel KE, Shen DD, Podoll TD, Kunze KL, Trager WF, Bacchi CE, Marsh CL, McVicar JP, Barr DM, Perkins JD, et al. Thummel KE, et al. J Pharmacol Exp Ther. 1994 Oct;271(1):557-66. J Pharmacol Exp Ther. 1994. PMID: 7965756

6

Human liver microsomal enflurane defluorination catalyzed by cytochrome P-450 2E1.

Thummel KE, Kharasch ED, Podoll T, Kunze K. Thummel KE, et al. Drug Metab Dispos. 1993 Mar-Apr;21(2):350-7. Drug Metab Dispos. 1993. PMID: 8097708

7

Human alfentanil metabolism by cytochrome P450 3A3/4. An explanation for the interindividual variability in alfentanil clearance?

Kharasch ED, Thummel KE. Kharasch ED, et al. Among authors: thummel ke. Anesth Analg. 1993 May;76(5):1033-9. doi: 10.1213/00000539-199305000-00022. Anesth Analg. 1993. PMID: 8484504

8

Stereoselective metabolism of enflurane by human liver cytochrome P450 2E1.

Garton KJ, Yuen P, Meinwald J, Thummel KE, Kharasch ED. Garton KJ, et al. Among authors: thummel ke. Drug Metab Dispos. 1995 Dec;23(12):1426-30. Drug Metab Dispos. 1995. PMID: 8689955

9

Warfarin-fluconazole. I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies.

Kunze KL, Wienkers LC, Thummel KE, Trager WF. Kunze KL, et al. Among authors: thummel ke. Drug Metab Dispos. 1996 Apr;24(4):414-21. Drug Metab Dispos. 1996. PMID: 8801056

10

Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.

Spracklin DK, Thummel KE, Kharasch ED. Spracklin DK, et al. Among authors: thummel ke. Drug Metab Dispos. 1996 Sep;24(9):976-83. Drug Metab Dispos. 1996. PMID: 8886607

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