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Assessment of the clinical effects of cholesteryl ester transfer protein inhibition with evacetrapib in patients at high-risk for vascular outcomes: Rationale and design of the ACCELERATE trial.
Nicholls SJ, Lincoff AM, Barter PJ, Brewer HB, Fox KA, Gibson CM, Grainger C, Menon V, Montalescot G, Rader D, Tall AR, McErlean E, Riesmeyer J, Vangerow B, Ruotolo G, Weerakkody GJ, Nissen SE. Nicholls SJ, et al. Among authors: rader d. Am Heart J. 2015 Dec;170(6):1061-9. doi: 10.1016/j.ahj.2015.09.007. Epub 2015 Sep 16. Am Heart J. 2015. PMID: 26678626 Clinical Trial.
Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease.
Lincoff AM, Nicholls SJ, Riesmeyer JS, Barter PJ, Brewer HB, Fox KAA, Gibson CM, Granger C, Menon V, Montalescot G, Rader D, Tall AR, McErlean E, Wolski K, Ruotolo G, Vangerow B, Weerakkody G, Goodman SG, Conde D, McGuire DK, Nicolau JC, Leiva-Pons JL, Pesant Y, Li W, Kandath D, Kouz S, Tahirkheli N, Mason D, Nissen SE; ACCELERATE Investigators. Lincoff AM, et al. Among authors: rader d. N Engl J Med. 2017 May 18;376(20):1933-1942. doi: 10.1056/NEJMoa1609581. N Engl J Med. 2017. PMID: 28514624 Free article. Clinical Trial.
A Translational Medicine perspective of the development of torcetrapib: Does the failure of torcetrapib development cast a shadow on future development of lipid modifying agents, HDL elevation strategies or CETP as a viable molecular target for atherosclerosis? A case study of the use of biomarkers and Translational Medicine in atherosclerosis drug discovery and development.
Zhao L, Jin W, Rader D, Packard C, Feuerstein G. Zhao L, et al. Among authors: rader d. Biochem Pharmacol. 2009 Aug 15;78(4):315-25. doi: 10.1016/j.bcp.2009.03.014. Epub 2009 Mar 24. Biochem Pharmacol. 2009. PMID: 19539799
HDL cholesterol efflux capacity and incident cardiovascular events.
Rohatgi A, Khera A, Berry JD, Givens EG, Ayers CR, Wedin KE, Neeland IJ, Yuhanna IS, Rader DR, de Lemos JA, Shaul PW. Rohatgi A, et al. Among authors: rader dr. N Engl J Med. 2014 Dec 18;371(25):2383-93. doi: 10.1056/NEJMoa1409065. Epub 2014 Nov 18. N Engl J Med. 2014. PMID: 25404125 Free PMC article.
HIV-related lipodystrophy and related factors.
Tershakovec AM, Frank I, Rader D. Tershakovec AM, et al. Among authors: rader d. Atherosclerosis. 2004 May;174(1):1-10. doi: 10.1016/S0021-9150(03)00246-6. Atherosclerosis. 2004. PMID: 15135244 Review.
Human genetics identify convergent signals in mitochondrial LACTB-mediated lipid metabolism in cardiovascular-kidney-metabolic syndrome.
Li S, Liu H, Hu H, Ha E, Prasad P, Jenkins BC, Das US, Mukherjee S, Shishikura K, Hu R, Rader DJ, Pei L, Baur JA, Matthews ML, FitzGerald GA, McReynolds MR, Susztak K. Li S, et al. Among authors: rader dj. Cell Metab. 2024 Nov 14:S1550-4131(24)00403-0. doi: 10.1016/j.cmet.2024.10.007. Online ahead of print. Cell Metab. 2024. PMID: 39561766
Evaluating Performance and Agreement of Coronary Heart Disease Polygenic Risk Scores.
Abramowitz SA, Boulier K, Keat K, Cardone KM, Shivakumar M, DePaolo J, Judy R, Bermudez F, Mimouni N, Neylan C, Kim D, Rader DJ, Ritchie MD, Voight BF, Pasaniuc B, Levin MG, Damrauer SM; Penn Medicine BioBank. Abramowitz SA, et al. Among authors: rader dj. JAMA. 2024 Nov 16:e2423784. doi: 10.1001/jama.2024.23784. Online ahead of print. JAMA. 2024. PMID: 39549270
1,047 results