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A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke.
Maysami S, Wong R, Pradillo JM, Denes A, Dhungana H, Malm T, Koistinaho J, Orset C, Rahman M, Rubio M, Schwaninger M, Vivien D, Bath PM, Rothwell NJ, Allan SM. Maysami S, et al. Among authors: rothwell nj. J Cereb Blood Flow Metab. 2016 Mar;36(3):596-605. doi: 10.1177/0271678X15606714. Epub 2015 Sep 30. J Cereb Blood Flow Metab. 2016. PMID: 26661169 Free PMC article.
Platelet interleukin-1alpha drives cerebrovascular inflammation.
Thornton P, McColl BW, Greenhalgh A, Denes A, Allan SM, Rothwell NJ. Thornton P, et al. Among authors: rothwell nj. Blood. 2010 Apr 29;115(17):3632-9. doi: 10.1182/blood-2009-11-252643. Epub 2010 Mar 3. Blood. 2010. PMID: 20200351 Free article.
Delayed administration of interleukin-1 receptor antagonist reduces ischemic brain damage and inflammation in comorbid rats.
Pradillo JM, Denes A, Greenhalgh AD, Boutin H, Drake C, McColl BW, Barton E, Proctor SD, Russell JC, Rothwell NJ, Allan SM. Pradillo JM, et al. Among authors: rothwell nj. J Cereb Blood Flow Metab. 2012 Sep;32(9):1810-9. doi: 10.1038/jcbfm.2012.101. Epub 2012 Jul 11. J Cereb Blood Flow Metab. 2012. PMID: 22781338 Free PMC article.
The acute-phase protein PTX3 is an essential mediator of glial scar formation and resolution of brain edema after ischemic injury.
Rodriguez-Grande B, Swana M, Nguyen L, Englezou P, Maysami S, Allan SM, Rothwell NJ, Garlanda C, Denes A, Pinteaux E. Rodriguez-Grande B, et al. Among authors: rothwell nj. J Cereb Blood Flow Metab. 2014 Mar;34(3):480-8. doi: 10.1038/jcbfm.2013.224. Epub 2013 Dec 18. J Cereb Blood Flow Metab. 2014. PMID: 24346689 Free PMC article.
394 results