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Meeting the challenge of predicting hepatic clearance of compounds slowly metabolized by cytochrome P450 using a novel hepatocyte model, HepatoPac.
Chan TS, Yu H, Moore A, Khetani SR, Tweedie D. Chan TS, et al. Among authors: moore a. Drug Metab Dispos. 2013 Dec;41(12):2024-32. doi: 10.1124/dmd.113.053397. Epub 2013 Aug 19. Drug Metab Dispos. 2013. Corrected and republished in: Drug Metab Dispos. 2019 Jan;47(1):58-66. doi: 10.1124/dmd.113.053397fullarticlecorrection PMID: 23959596 Corrected and republished.
Long-term stability of primary rat hepatocytes in micropatterned cocultures.
Ukairo O, Kanchagar C, Moore A, Shi J, Gaffney J, Aoyama S, Rose K, Krzyzewski S, McGeehan J, Andersen ME, Khetani SR, Lecluyse EL. Ukairo O, et al. Among authors: moore a. J Biochem Mol Toxicol. 2013 Mar;27(3):204-12. doi: 10.1002/jbt.21469. Epub 2013 Jan 11. J Biochem Mol Toxicol. 2013. PMID: 23315828
6,789 results