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Page 1
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.
de Waal L, Lewis TA, Rees MG, Tsherniak A, Wu X, Choi PS, Gechijian L, Hartigan C, Faloon PW, Hickey MJ, Tolliday N, Carr SA, Clemons PA, Munoz B, Wagner BK, Shamji AF, Koehler AN, Schenone M, Burgin AB, Schreiber SL, Greulich H, Meyerson M. de Waal L, et al. Among authors: faloon pw. Nat Chem Biol. 2016 Feb;12(2):102-8. doi: 10.1038/nchembio.1984. Epub 2015 Dec 14. Nat Chem Biol. 2016. PMID: 26656089 Free PMC article.
Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling.
Chou DH, Vetere A, Choudhary A, Scully SS, Schenone M, Tang A, Gomez R, Burns SM, Lundh M, Vital T, Comer E, Faloon PW, Dančík V, Ciarlo C, Paulk J, Dai M, Reddy C, Sun H, Young M, Donato N, Jaffe J, Clemons PA, Palmer M, Carr SA, Schreiber SL, Wagner BK. Chou DH, et al. Among authors: faloon pw. J Am Chem Soc. 2015 Jun 24;137(24):7929-34. doi: 10.1021/jacs.5b04284. Epub 2015 Jun 15. J Am Chem Soc. 2015. PMID: 26042473 Free PMC article.
Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake.
Dockendorff C, Faloon PW, Pu J, Yu M, Johnston S, Bennion M, Penman M, Nieland TJ, Dandapani S, Perez JR, Munoz B, Palmer MA, Schreiber SL, Krieger M. Dockendorff C, et al. Among authors: faloon pw. Bioorg Med Chem Lett. 2015;25(10):2100-5. doi: 10.1016/j.bmcl.2015.03.073. Epub 2015 Apr 1. Bioorg Med Chem Lett. 2015. PMID: 25900219 Free PMC article.
Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport.
Dockendorff C, Faloon PW, Yu M, Youngsaye W, Penman M, Nieland TJ, Nag PP, Lewis TA, Pu J, Bennion M, Negri J, Paterson C, Lam G, Dandapani S, Perez JR, Munoz B, Palmer MA, Schreiber SL, Krieger M. Dockendorff C, et al. Among authors: faloon pw. ACS Med Chem Lett. 2015 Feb 2;6(4):375-380. doi: 10.1021/ml500154q. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 26478787 Free PMC article.
Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake.
Dockendorff C, Faloon PW, Germain A, Yu M, Youngsaye W, Nag PP, Bennion M, Penman M, Nieland TJ, Dandapani S, Perez JR, Munoz B, Palmer MA, Schreiber SL, Krieger M. Dockendorff C, et al. Among authors: faloon pw. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2594-8. doi: 10.1016/j.bmcl.2015.03.074. Epub 2015 Apr 11. Bioorg Med Chem Lett. 2015. PMID: 25958245 Free PMC article.
Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic Treatment.
Weïwer M, Xu Q, Gale JP, Lewis M, Campbell AJ, Schroeder FA, Van de Bittner GC, Walk M, Amaya A, Su P, D Ordevic L, Sacher JR, Skepner A, Fei D, Dennehy K, Nguyen S, Faloon PW, Perez J, Cottrell JR, Liu F, Palmer M, Pan JQ, Hooker JM, Zhang YL, Scolnick E, Wagner FF, Holson EB. Weïwer M, et al. Among authors: faloon pw. ACS Chem Biol. 2018 Apr 20;13(4):1038-1047. doi: 10.1021/acschembio.8b00168. Epub 2018 Mar 14. ACS Chem Biol. 2018. PMID: 29485852
A Small Molecule Inhibitor of the MITF Molecular Pathway.
Faloon PW, Bennion M, Weiner WS, Smith RA, Wurst J, Weiwer M, Hartland C, Mosher CM, Johnston S, Porubsky P, Neuenswander B, Dandapani S, Munoz B, Schoenen FJ, Metkar S, Haq R, Fisher DE, Aubé J, Palmer M, Schreiber SL. Faloon PW, et al. 2012 Dec 13 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Dec 13 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 24027801 Free Books & Documents. Review.
A Small Molecule Inhibitor of Scavenger Receptor BI-mediated Lipid Uptake—Probe 2.
Faloon PW, Dockendorff C, Germain A, Yu M, Nag PP, Youngsaye W, Bennion M, Lam G, Paterson C, Dandapani S, Munoz B, Perez J, Palmer M, Nieland TJF, Krieger M, Schreiber SL. Faloon PW, et al. 2011 Dec 15 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2011 Dec 15 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23658957 Free Books & Documents. Review.
16 results