Smith GA - Search Results

1

Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex.

Carelli JD, Sethofer SG, Smith GA, Miller HR, Simard JL, Merrick WC, Jain RK, Ross NT, Taunton J. Carelli JD, et al. Among authors: smith ga. Elife. 2015 Dec 10;4:e10222. doi: 10.7554/eLife.10222. Elife. 2015. PMID: 26651998 Free PMC article.

2

Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling.

Smith GA, Uchida K, Weiss A, Taunton J. Smith GA, et al. Nat Chem Biol. 2016 May;12(5):373-9. doi: 10.1038/nchembio.2056. Epub 2016 Mar 28. Nat Chem Biol. 2016. PMID: 27018889 Free PMC article.

3

Regulation of B cell fate by chronic activity of the IgE B cell receptor.

Yang Z, Robinson MJ, Chen X, Smith GA, Taunton J, Liu W, Allen CD. Yang Z, et al. Among authors: smith ga. Elife. 2016 Dec 9;5:e21238. doi: 10.7554/eLife.21238. Elife. 2016. PMID: 27935477 Free PMC article.

4

JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias.

Delgado-Martin C, Meyer LK, Huang BJ, Shimano KA, Zinter MS, Nguyen JV, Smith GA, Taunton J, Winter SS, Roderick JR, Kelliher MA, Horton TM, Wood BL, Teachey DT, Hermiston ML. Delgado-Martin C, et al. Among authors: smith ga. Leukemia. 2017 Dec;31(12):2568-2576. doi: 10.1038/leu.2017.136. Epub 2017 May 9. Leukemia. 2017. PMID: 28484265 Free PMC article.

5

IL-2Rβ abundance differentially tunes IL-2 signaling dynamics in CD4⁺ and CD8⁺ T cells.

Smith GA, Taunton J, Weiss A. Smith GA, et al. Sci Signal. 2017 Dec 19;10(510):eaan4931. doi: 10.1126/scisignal.aan4931. Sci Signal. 2017. PMID: 29259099 Free PMC article.

6

Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment.

Lam C, Ferguson ID, Mariano MC, Lin YT, Murnane M, Liu H, Smith GA, Wong SW, Taunton J, Liu JO, Mitsiades CS, Hann BC, Aftab BT, Wiita AP. Lam C, et al. Among authors: smith ga. Haematologica. 2018 Jul;103(7):1218-1228. doi: 10.3324/haematol.2017.174482. Epub 2018 Apr 5. Haematologica. 2018. PMID: 29622655 Free PMC article.

7

New treatments for breast cancer.

Smith G, Henderson IC. Smith G, et al. Semin Oncol. 1996 Aug;23(4):506-28. Semin Oncol. 1996. PMID: 8757276 Review.

8

Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor.

Smith GA, Padmanabhan A, Lau BH, Pampana A, Li L, Lee CY, Pelonero A, Nishino T, Sadagopan N, Xia VQ, Jain R, Natarajan P, Wu RS, Black BL, Srivastava D, Shokat KM, Chorba JS. Smith GA, et al. Sci Transl Med. 2022 Sep 14;14(662):eabj8670. doi: 10.1126/scitranslmed.abj8670. Epub 2022 Sep 14. Sci Transl Med. 2022. PMID: 36103516 Free PMC article.

9

Can the famous really postpone death?

Royer H, Smith G. Royer H, et al. Soc Biol. 1998 Fall-Winter;45(3-4):302-5. doi: 10.1080/19485565.1998.9988981. Soc Biol. 1998. PMID: 10085742

10

IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level.

Au-Yeung BB, Smith GA, Mueller JL, Heyn CS, Jaszczak RG, Weiss A, Zikherman J. Au-Yeung BB, et al. Among authors: smith ga. J Immunol. 2017 Mar 15;198(6):2445-2456. doi: 10.4049/jimmunol.1601453. Epub 2017 Feb 3. J Immunol. 2017. PMID: 28159902 Free PMC article.

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