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N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators.
J Med Chem. 2016 Jan 14;59(1):61-81. doi: 10.1021/acs.jmedchem.5b01239. Epub 2015 Dec 25.
J Med Chem. 2016.
PMID: 26595749
Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ.
Göbel T, Diehl O, Heering J, Merk D, Angioni C, Wittmann SK, Buscato E, Kottke R, Weizel L, Schader T, Maier TJ, Geisslinger G, Schubert-Zsilavecz M, Steinhilber D, Proschak E, Kahnt AS.
Göbel T, et al. Among authors: schader t.
Front Pharmacol. 2019 Mar 20;10:263. doi: 10.3389/fphar.2019.00263. eCollection 2019.
Front Pharmacol. 2019.
PMID: 30949053
Free PMC article.
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NoxO1 Knockout Promotes Longevity in Mice.
Schader T, Reschke C, Spaeth M, Wienstroer S, Wong S, Schröder K.
Schader T, et al.
Antioxidants (Basel). 2020 Mar 10;9(3):226. doi: 10.3390/antiox9030226.
Antioxidants (Basel). 2020.
PMID: 32164269
Free PMC article.
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Oxidation of HDAC4 by Nox4-derived H2O2 maintains tube formation by endothelial cells.
Schader T, Löwe O, Reschke C, Malacarne P, Hahner F, Müller N, Gajos-Draus A, Backs J, Schröder K.
Schader T, et al.
Redox Biol. 2020 Sep;36:101669. doi: 10.1016/j.redox.2020.101669. Epub 2020 Aug 2.
Redox Biol. 2020.
PMID: 32818796
Free PMC article.
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Nox4 promotes endothelial differentiation through chromatin remodeling.
Hahner F, Moll F, Warwick T, Hebchen DM, Buchmann GK, Epah J, Abplanalp W, Schader T, Günther S, Gilsbach R, Brandes RP, Schröder K.
Hahner F, et al. Among authors: schader t.
Redox Biol. 2022 Sep;55:102381. doi: 10.1016/j.redox.2022.102381. Epub 2022 Jul 6.
Redox Biol. 2022.
PMID: 35810713
Free PMC article.
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Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and treatment resistance.
Spinner S, Crispatzu G, Yi JH, Munkhbaatar E, Mayer P, Höckendorf U, Müller N, Li Z, Schader T, Bendz H, Hartmann S, Yabal M, Pechloff K, Heikenwalder M, Kelly GL, Strasser A, Peschel C, Hansmann ML, Ruland J, Keller U, Newrzela S, Herling M, Jost PJ.
Spinner S, et al. Among authors: schader t.
Leukemia. 2016 Jul;30(7):1520-30. doi: 10.1038/leu.2016.49. Epub 2016 Mar 8.
Leukemia. 2016.
PMID: 27055871
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