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Page 1
An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish.
Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC. Zou J, et al. Among authors: pelonero a. Elife. 2015 Oct 16;4:e09406. doi: 10.7554/eLife.09406. Elife. 2015. PMID: 26473617 Free PMC article.
Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor.
Smith GA, Padmanabhan A, Lau BH, Pampana A, Li L, Lee CY, Pelonero A, Nishino T, Sadagopan N, Xia VQ, Jain R, Natarajan P, Wu RS, Black BL, Srivastava D, Shokat KM, Chorba JS. Smith GA, et al. Among authors: pelonero a. Sci Transl Med. 2022 Sep 14;14(662):eabj8670. doi: 10.1126/scitranslmed.abj8670. Epub 2022 Sep 14. Sci Transl Med. 2022. PMID: 36103516 Free PMC article.
A transcriptional switch governs fibroblast activation in heart disease.
Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D. Alexanian M, et al. Among authors: pelonero a. Nature. 2021 Jul;595(7867):438-443. doi: 10.1038/s41586-021-03674-1. Epub 2021 Jun 23. Nature. 2021. PMID: 34163071 Free PMC article.
Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors.
Zhu L, Choudhary K, Gonzalez-Teran B, Ang YS, Thomas R, Stone NR, Liu L, Zhou P, Zhu C, Ruan H, Huang Y, Jin S, Pelonero A, Koback F, Padmanabhan A, Sadagopan N, Hsu A, Costa MW, Gifford CA, van Bemmel JG, Hüttenhain R, Vedantham V, Conklin BR, Black BL, Bruneau BG, Steinmetz L, Krogan NJ, Pollard KS, Srivastava D. Zhu L, et al. Among authors: pelonero a. Circulation. 2022 Sep 6;146(10):770-787. doi: 10.1161/CIRCULATIONAHA.121.057620. Epub 2022 Aug 8. Circulation. 2022. PMID: 35938400 Free PMC article.
Single Cell Multimodal Analyses Reveal Epigenomic and Transcriptomic Basis for Birth Defects in Maternal Diabetes.
Nishino T, Ranade SS, Pelonero A, van Soldt BJ, Ye L, Alexanian M, Koback F, Huang Y, Sadagopan N, Lam A, Zholudeva LV, Li F, Padmanabhan A, Thomas R, van Bemmel JG, Gifford CA, Costa MW, Srivastava D. Nishino T, et al. Among authors: pelonero a. Nat Cardiovasc Res. 2023 Dec;2(12):1190-1203. doi: 10.1038/s44161-023-00367-y. Epub 2023 Nov 30. Nat Cardiovasc Res. 2023. PMID: 39183978 Free PMC article.
Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Lee CY, Sadagopan N, Huang Y, Pelonero A, Auclair K, Zhu A, Teran BG, Flanigan W, Kim CK, Lumbao-Conradson K, Costa M, Jain R, Charo I, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. Among authors: pelonero a. bioRxiv [Preprint]. 2023 Jan 7:2023.01.06.522937. doi: 10.1101/2023.01.06.522937. bioRxiv. 2023. PMID: 36711864 Free PMC article. Preprint.
Chromatin remodelling drives immune cell-fibroblast communication in heart failure.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Pelonero A, Lee CY, Sadagopan N, Huang Y, Auclair K, Zhu A, An Y, Ekstrand CA, Martinez C, Teran BG, Flanigan WR, Kim CK, Lumbao-Conradson K, Gardner Z, Li L, Costa MW, Jain R, Charo I, Combes AJ, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. Among authors: pelonero a. Nature. 2024 Nov;635(8038):434-443. doi: 10.1038/s41586-024-08085-6. Epub 2024 Oct 23. Nature. 2024. PMID: 39443808
A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation.
Padmanabhan A, de Soysa TY, Pelonero A, Sapp V, Shah PP, Wang Q, Li L, Lee CY, Sadagopan N, Nishino T, Ye L, Yang R, Karnay A, Poleshko A, Bolar N, Linares-Saldana R, Ranade SS, Alexanian M, Morton SU, Jain M, Haldar SM, Srivastava D, Jain R. Padmanabhan A, et al. Among authors: pelonero a. Nat Cardiovasc Res. 2024 Mar;3(3):317-331. doi: 10.1038/s44161-024-00431-1. Epub 2024 Feb 23. Nat Cardiovasc Res. 2024. PMID: 39196112 Free PMC article.
The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5.
Maven BEJ, Gifford CA, Weilert M, Gonzalez-Teran B, Hüttenhain R, Pelonero A, Ivey KN, Samse-Knapp K, Kwong W, Gordon D, McGregor M, Nishino T, Okorie E, Rossman S, Costa MW, Krogan NJ, Zeitlinger J, Srivastava D. Maven BEJ, et al. Among authors: pelonero a. Stem Cell Reports. 2023 Nov 14;18(11):2138-2153. doi: 10.1016/j.stemcr.2023.09.014. Epub 2023 Oct 19. Stem Cell Reports. 2023. PMID: 37863045 Free PMC article.
26 results