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MiR-208a stimulates the cocktail of SOX2 and β-catenin to inhibit the let-7 induction of self-renewal repression of breast cancer stem cells and formed miR208a/let-7 feedback loop via LIN28 and DICER1.
Sun X, Jiang S, Liu J, Wang H, Zhang Y, Tang SC, Wang J, Du N, Xu C, Wang C, Qin S, Zhang J, Liu D, Zhang Y, Li X, Wang J, Dong J, Wang X, Xu S, Tao Z, Xu F, Zhou J, Wang T, Ren H. Sun X, et al. Oncotarget. 2015 Oct 20;6(32):32944-54. doi: 10.18632/oncotarget.5079. Oncotarget. 2015. PMID: 26460550 Free PMC article.
Possible carcinogenesis of tumor suppressor let-7.
Sun X, Fan C, Du N, Ren H. Sun X, et al. Med Hypotheses. 2013 Sep;81(3):410-3. doi: 10.1016/j.mehy.2013.05.033. Epub 2013 Jun 18. Med Hypotheses. 2013. PMID: 23790474
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