Hinderer C - Search Results

1

Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII.

Gurda BL, De Guilhem De Lataillade A, Bell P, Zhu Y, Yu H, Wang P, Bagel J, Vite CH, Sikora T, Hinderer C, Calcedo R, Yox AD, Steet RA, Ruane T, O'Donnell P, Gao G, Wilson JM, Casal M, Ponder KP, Haskins ME. Gurda BL, et al. Among authors: hinderer c. Mol Ther. 2016 Feb;24(2):206-216. doi: 10.1038/mt.2015.189. Epub 2015 Oct 8. Mol Ther. 2016. PMID: 26447927 Free PMC article.

2

Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis.

Kassim SH, Li H, Vandenberghe LH, Hinderer C, Bell P, Marchadier D, Wilson A, Cromley D, Redon V, Yu H, Wilson JM, Rader DJ. Kassim SH, et al. Among authors: hinderer c. PLoS One. 2010 Oct 19;5(10):e13424. doi: 10.1371/journal.pone.0013424. PLoS One. 2010. PMID: 20976059 Free PMC article.

3

Lessons learned from the clinical development and market authorization of Glybera.

Bryant LM, Christopher DM, Giles AR, Hinderer C, Rodriguez JL, Smith JB, Traxler EA, Tycko J, Wojno AP, Wilson JM. Bryant LM, et al. Among authors: hinderer c. Hum Gene Ther Clin Dev. 2013 Jun;24(2):55-64. doi: 10.1089/humc.2013.087. Epub 2013 Jun 29. Hum Gene Ther Clin Dev. 2013. PMID: 23808604 Free PMC article. Review.

4

Intrathecal gene therapy corrects CNS pathology in a feline model of mucopolysaccharidosis I.

Hinderer C, Bell P, Gurda BL, Wang Q, Louboutin JP, Zhu Y, Bagel J, O'Donnell P, Sikora T, Ruane T, Wang P, Haskins ME, Wilson JM. Hinderer C, et al. Mol Ther. 2014 Dec;22(12):2018-2027. doi: 10.1038/mt.2014.135. Epub 2014 Jul 16. Mol Ther. 2014. PMID: 25027660 Free PMC article.

5

Liver-directed gene therapy corrects cardiovascular lesions in feline mucopolysaccharidosis type I.

Hinderer C, Bell P, Gurda BL, Wang Q, Louboutin JP, Zhu Y, Bagel J, O'Donnell P, Sikora T, Ruane T, Wang P, Haskins ME, Wilson JM. Hinderer C, et al. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14894-9. doi: 10.1073/pnas.1413645111. Epub 2014 Sep 29. Proc Natl Acad Sci U S A. 2014. PMID: 25267637 Free PMC article.

6

Motor neuron transduction after intracisternal delivery of AAV9 in a cynomolgus macaque.

Bell P, Hinderer C, Louboutin JP, Yu H, Grant R, Bote E, Wilson JM. Bell P, et al. Among authors: hinderer c. Hum Gene Ther Methods. 2015 Apr;26(2):43-4. doi: 10.1089/hgtb.2015.041. Hum Gene Ther Methods. 2015. PMID: 25885277

7

Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman Primates.

Hinderer C, Bell P, Louboutin JP, Zhu Y, Yu H, Lin G, Choa R, Gurda BL, Bagel J, O'Donnell P, Sikora T, Ruane T, Wang P, Tarantal AF, Casal ML, Haskins ME, Wilson JM. Hinderer C, et al. Mol Ther. 2015 Aug;23(8):1298-1307. doi: 10.1038/mt.2015.99. Epub 2015 May 29. Mol Ther. 2015. PMID: 26022732 Free PMC article.

8

Widespread gene transfer in the central nervous system of cynomolgus macaques following delivery of AAV9 into the cisterna magna.

Hinderer C, Bell P, Vite CH, Louboutin JP, Grant R, Bote E, Yu H, Pukenas B, Hurst R, Wilson JM. Hinderer C, et al. Mol Ther Methods Clin Dev. 2014 Dec 10;1:14051. doi: 10.1038/mtm.2014.51. eCollection 2014. Mol Ther Methods Clin Dev. 2014. PMID: 26052519 Free PMC article.

9

Neonatal tolerance induction enables accurate evaluation of gene therapy for MPS I in a canine model.

Hinderer C, Bell P, Louboutin JP, Katz N, Zhu Y, Lin G, Choa R, Bagel J, O'Donnell P, Fitzgerald CA, Langan T, Wang P, Casal ML, Haskins ME, Wilson JM. Hinderer C, et al. Mol Genet Metab. 2016 Sep;119(1-2):124-30. doi: 10.1016/j.ymgme.2016.06.006. Epub 2016 Jun 8. Mol Genet Metab. 2016. PMID: 27386755 Free PMC article.

10

Delivery of an Adeno-Associated Virus Vector into Cerebrospinal Fluid Attenuates Central Nervous System Disease in Mucopolysaccharidosis Type II Mice.

Hinderer C, Katz N, Louboutin JP, Bell P, Yu H, Nayal M, Kozarsky K, O'Brien WT, Goode T, Wilson JM. Hinderer C, et al. Hum Gene Ther. 2016 Nov;27(11):906-915. doi: 10.1089/hum.2016.101. Epub 2016 Aug 10. Hum Gene Ther. 2016. PMID: 27510804

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