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Omega-3 Fatty Acids Increase Amyloid-β Immunity, Energy, and Circadian Rhythm for Cognitive Protection of Alzheimer's Disease Patients Beyond Cholinesterase Inhibitors.
Fiala M, Lau YCC, Aghajani A, Bhargava S, Aminpour E, Kaczor-Urbanowicz KE, Mirzoyan H, Nichols I, Ko MW, Morselli M, Santana J, Dang J, Sayre J, Paul K, Pellegrini M. Fiala M, et al. J Alzheimers Dis. 2020;75(3):993-1002. doi: 10.3233/JAD-200252. J Alzheimers Dis. 2020. PMID: 32390637 Free PMC article.
Modulation of innate immunity of patients with Alzheimer's disease by omega-3 fatty acids.
Fiala M, Kooij G, Wagner K, Hammock B, Pellegrini M. Fiala M, et al. FASEB J. 2017 Aug;31(8):3229-3239. doi: 10.1096/fj.201700065R. Epub 2017 Apr 18. FASEB J. 2017. PMID: 28420693 Free PMC article. Review.
Therefore, accumulating preclinical and preliminary clinical evidence indicates that omega-3 supplementation should be tested in a randomized controlled clinical trial and that the analysis should involve the apolipoprotein E genotype and intervening conditions during trial.-F
Therefore, accumulating preclinical and preliminary clinical evidence indicates that omega-3 supplementation should be tested in a randomize …
Omega-3 fatty acids increase the unfolded protein response and improve amyloid-β phagocytosis by macrophages of patients with mild cognitive impairment.
Olivera-Perez HM, Lam L, Dang J, Jiang W, Rodriguez F, Rigali E, Weitzman S, Porter V, Rubbi L, Morselli M, Pellegrini M, Fiala M. Olivera-Perez HM, et al. Among authors: fiala m. FASEB J. 2017 Oct;31(10):4359-4369. doi: 10.1096/fj.201700290R. Epub 2017 Jun 20. FASEB J. 2017. PMID: 28634213 Free PMC article.
Patients in the apolipoprotein E (ApoE)e3/e3 subgroup over time exhibited an increase of protein kinase RNA-like ER kinase (PERK) expression, Abeta phagocytosis, intermediate M1-M2 M type, and a Mini-Mental State Examination (MMSE) rate of change of +1.8 points per year, w …
Patients in the apolipoprotein E (ApoE)e3/e3 subgroup over time exhibited an increase of protein kinase RNA-like ER kinase (PERK) expression …
373 results