Manning Fox JE - Search Results

1

Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells.

Ferdaoussi M, Dai X, Jensen MV, Wang R, Peterson BS, Huang C, Ilkayeva O, Smith N, Miller N, Hajmrle C, Spigelman AF, Wright RC, Plummer G, Suzuki K, Mackay JP, van de Bunt M, Gloyn AL, Ryan TE, Norquay LD, Brosnan MJ, Trimmer JK, Rolph TP, Kibbey RG, Manning Fox JE, Colmers WF, Shirihai OS, Neufer PD, Yeh ET, Newgard CB, MacDonald PE. Ferdaoussi M, et al. Among authors: manning fox je. J Clin Invest. 2015 Oct 1;125(10):3847-60. doi: 10.1172/JCI82498. Epub 2015 Sep 21. J Clin Invest. 2015. PMID: 26389676 Free PMC article.

2

Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells.

Pigeau GM, Kolic J, Ball BJ, Hoppa MB, Wang YW, Rückle T, Woo M, Manning Fox JE, MacDonald PE. Pigeau GM, et al. Among authors: manning fox je. Diabetes. 2009 Sep;58(9):2084-92. doi: 10.2337/db08-1371. Epub 2009 Jun 23. Diabetes. 2009. PMID: 19549714 Free PMC article.

3

SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.

Dai XQ, Plummer G, Casimir M, Kang Y, Hajmrle C, Gaisano HY, Manning Fox JE, MacDonald PE. Dai XQ, et al. Among authors: manning fox je. Diabetes. 2011 Mar;60(3):838-47. doi: 10.2337/db10-0440. Epub 2011 Jan 24. Diabetes. 2011. PMID: 21266332 Free PMC article.

4

Novel roles of SUMO in pancreatic β-cells: thinking outside the nucleus.

Manning Fox JE, Hajmrle C, Macdonald PE. Manning Fox JE, et al. Can J Physiol Pharmacol. 2012 Jun;90(6):765-70. doi: 10.1139/y11-134. Epub 2012 Apr 9. Can J Physiol Pharmacol. 2012. PMID: 22486776 Review.

5

Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion.

Yang YH, Manning Fox JE, Zhang KL, MacDonald PE, Johnson JD. Yang YH, et al. Among authors: manning fox je. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16480-5. doi: 10.1073/pnas.1214312110. Epub 2013 Sep 24. Proc Natl Acad Sci U S A. 2013. PMID: 24065825 Free PMC article.

6

Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretion.

Patterson JN, Cousteils K, Lou JW, Manning Fox JE, MacDonald PE, Joseph JW. Patterson JN, et al. Among authors: manning fox je. J Biol Chem. 2014 May 9;289(19):13335-46. doi: 10.1074/jbc.M113.521666. Epub 2014 Mar 27. J Biol Chem. 2014. PMID: 24675076 Free PMC article.

7

SUMO1 enhances cAMP-dependent exocytosis and glucagon secretion from pancreatic α-cells.

Dai XQ, Spigelman AF, Khan S, Braun M, Manning Fox JE, MacDonald PE. Dai XQ, et al. Among authors: manning fox je. J Physiol. 2014 Sep 1;592(17):3715-26. doi: 10.1113/jphysiol.2014.274084. Epub 2014 Jun 6. J Physiol. 2014. PMID: 24907310 Free PMC article.

8

SUMOylation protects against IL-1β-induced apoptosis in INS-1 832/13 cells and human islets.

Hajmrle C, Ferdaoussi M, Plummer G, Spigelman AF, Lai K, Manning Fox JE, MacDonald PE. Hajmrle C, et al. Among authors: manning fox je. Am J Physiol Endocrinol Metab. 2014 Oct 15;307(8):E664-73. doi: 10.1152/ajpendo.00168.2014. Epub 2014 Aug 19. Am J Physiol Endocrinol Metab. 2014. PMID: 25139051 Free PMC article.

9

Insulin secretion induced by glucose-dependent insulinotropic polypeptide requires phosphatidylinositol 3-kinase γ in rodent and human β-cells.

Kolic J, Spigelman AF, Smith AM, Manning Fox JE, MacDonald PE. Kolic J, et al. Among authors: manning fox je. J Biol Chem. 2014 Nov 14;289(46):32109-32120. doi: 10.1074/jbc.M114.577510. Epub 2014 Oct 6. J Biol Chem. 2014. PMID: 25288806 Free PMC article.

10

Human islet function following 20 years of cryogenic biobanking.

Manning Fox JE, Lyon J, Dai XQ, Wright RC, Hayward J, van de Bunt M, Kin T, Shapiro AM, McCarthy MI, Gloyn AL, Ungrin MD, Lakey JR, Kneteman NM, Warnock GL, Korbutt GS, Rajotte RV, MacDonald PE. Manning Fox JE, et al. Diabetologia. 2015 Jul;58(7):1503-12. doi: 10.1007/s00125-015-3598-4. Epub 2015 May 1. Diabetologia. 2015. PMID: 25930156 Free PMC article.

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