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Type I and type II Fc receptors regulate innate and adaptive immunity.
Pincetic A, Bournazos S, DiLillo DJ, Maamary J, Wang TT, Dahan R, Fiebiger BM, Ravetch JV. Pincetic A, et al. Among authors: dahan r. Nat Immunol. 2014 Aug;15(8):707-16. doi: 10.1038/ni.2939. Nat Immunol. 2014. PMID: 25045879 Free PMC article. Review.
Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis.
Georgoudaki AM, Prokopec KE, Boura VF, Hellqvist E, Sohn S, Östling J, Dahan R, Harris RA, Rantalainen M, Klevebring D, Sund M, Brage SE, Fuxe J, Rolny C, Li F, Ravetch JV, Karlsson MC. Georgoudaki AM, et al. Among authors: dahan r. Cell Rep. 2016 May 31;15(9):2000-11. doi: 10.1016/j.celrep.2016.04.084. Epub 2016 May 19. Cell Rep. 2016. PMID: 27210762 Free article.
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.
Arce Vargas F, Furness AJS, Solomon I, Joshi K, Mekkaoui L, Lesko MH, Miranda Rota E, Dahan R, Georgiou A, Sledzinska A, Ben Aissa A, Franz D, Werner Sunderland M, Wong YNS, Henry JY, O'Brien T, Nicol D, Challacombe B, Beers SA; Melanoma TRACERx Consortium; Renal TRACERx Consortium; Lung TRACERx Consortium; Turajlic S, Gore M, Larkin J, Swanton C, Chester KA, Pule M, Ravetch JV, Marafioti T, Peggs KS, Quezada SA. Arce Vargas F, et al. Among authors: dahan r. Immunity. 2017 Apr 18;46(4):577-586. doi: 10.1016/j.immuni.2017.03.013. Epub 2017 Apr 11. Immunity. 2017. PMID: 28410988 Free PMC article.
Signaling by Antibodies: Recent Progress.
Bournazos S, Wang TT, Dahan R, Maamary J, Ravetch JV. Bournazos S, et al. Among authors: dahan r. Annu Rev Immunol. 2017 Apr 26;35:285-311. doi: 10.1146/annurev-immunol-051116-052433. Annu Rev Immunol. 2017. PMID: 28446061 Free PMC article. Review.
FcyRIIB is a novel immune checkpoint in the tumor microenvironment limiting activity of Treg-targeting antibodies.
Knorr D, Leidner R, Jensen S, Meng R, Jones A, Ballesteros-Merino C, Bell RB, Baez M, Sprott D, Bifulco C, Piening B, Dahan R, Fox BA, Ravetch J. Knorr D, et al. Among authors: dahan r. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.522856. doi: 10.1101/2023.01.19.522856. bioRxiv. 2023. Update in: Cancer Immunol Res. 2024 Mar 4;12(3):322-333. doi: 10.1158/2326-6066.CIR-23-0389. PMID: 36711504 Free PMC article. Updated. Preprint.
124 results