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Page 1
The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species.
McLaren DG, He T, Wang SP, Mendoza V, Rosa R, Gagen K, Bhat G, Herath K, Miller PL, Stribling S, Taggart A, Imbriglio J, Liu J, Chen D, Pinto S, Balkovec JM, DeVita RJ, Marsh DJ, Castro-Perez JM, Strack A, Johns DG, Previs SF, Hubbard BK, Roddy TP. McLaren DG, et al. Among authors: previs sf. J Lipid Res. 2011 Jun;52(6):1150-1161. doi: 10.1194/jlr.M011049. Epub 2011 Mar 17. J Lipid Res. 2011. PMID: 21415123 Free PMC article.
Attenuation of Slc27a5 gene expression followed by LC-MS measurement of bile acid reconjugation using metabolomics and a stable isotope tracer strategy.
Castro-Perez JM, Roddy TP, Shah V, Wang SP, Ouyang X, Ogawa A, McLaren DG, Tadin-Strapps M, Robinson MJ, Bartz SR, Ason B, Chen Y, Previs SF, Wong KK, Vreeken RJ, Johns DG, Hubbard BK, Hankemeier T, Mitnaul L. Castro-Perez JM, et al. Among authors: previs sf. J Proteome Res. 2011 Oct 7;10(10):4683-91. doi: 10.1021/pr200475g. Epub 2011 Aug 26. J Proteome Res. 2011. PMID: 21819150
Use of [13C18] oleic acid and mass isotopomer distribution analysis to study synthesis of plasma triglycerides in vivo: analytical and experimental considerations.
McLaren DG, Cardasis HL, Stout SJ, Wang SP, Mendoza V, Castro-Perez JM, Miller PL, Murphy BA, Cumiskey AM, Cleary MA, Johns DG, Previs SF, Roddy TP. McLaren DG, et al. Among authors: previs sf. Anal Chem. 2013 Jul 2;85(13):6287-94. doi: 10.1021/ac400363k. Epub 2013 Jun 10. Anal Chem. 2013. PMID: 23668715
Determination of low levels of 2H-labeling using high-resolution mass spectrometry: application in studies of lipid flux and beyond.
Herath KB, Zhong W, Yang J, Mahsut A, Rohm RJ, Shah V, Castro-Perez J, Zhou H, Attygalle AB, Kang L, Singh S, Johns DG, Cleary MA, Hubbard BK, Previs SF, Roddy TP. Herath KB, et al. Among authors: previs sf. Rapid Commun Mass Spectrom. 2014 Feb 15;28(3):239-44. doi: 10.1002/rcm.6776. Rapid Commun Mass Spectrom. 2014. PMID: 24375874
Enhancing Studies of Pharmacodynamic Mechanisms via Measurements of Metabolic Flux: Fundamental Concepts and Guiding Principles for Using Stable Isotope Tracers.
Daurio NA, Wang SP, Chen Y, Zhou H, McLaren DG, Roddy TP, Johns DG, Milot D, Kasumov T, Erion MD, Kelley DE, Previs SF. Daurio NA, et al. Among authors: previs sf. J Pharmacol Exp Ther. 2017 Oct;363(1):80-91. doi: 10.1124/jpet.117.241091. Epub 2017 Jul 19. J Pharmacol Exp Ther. 2017. PMID: 28724692 Review.
In vivo isotopically labeled atherosclerotic aorta plaques in ApoE KO mice and molecular profiling by matrix-assisted laser desorption/ionization mass spectrometric imaging.
Castro-Perez J, Hatcher N, Kofi Karikari N, Wang SP, Mendoza V, Shion H, Millar A, Shockcor J, Towers M, McLaren D, Shah V, Previs S, Akinsanya K, Cleary M, Roddy TP, Johns DG. Castro-Perez J, et al. Rapid Commun Mass Spectrom. 2014 Nov 30;28(22):2471-9. doi: 10.1002/rcm.7039. Rapid Commun Mass Spectrom. 2014. PMID: 25303476
151 results