Borisov N - Search Results

1

A method for predicting target drug efficiency in cancer based on the analysis of signaling pathway activation.

Artemov A, Aliper A, Korzinkin M, Lezhnina K, Jellen L, Zhukov N, Roumiantsev S, Gaifullin N, Zhavoronkov A, Borisov N, Buzdin A. Artemov A, et al. Among authors: borisov n. Oncotarget. 2015 Oct 6;6(30):29347-56. doi: 10.18632/oncotarget.5119. Oncotarget. 2015. PMID: 26320181 Free PMC article.

2

Silencing AML1-ETO gene expression leads to simultaneous activation of both pro-apoptotic and proliferation signaling.

Spirin PV, Lebedev TD, Orlova NN, Gornostaeva AS, Prokofjeva MM, Nikitenko NA, Dmitriev SE, Buzdin AA, Borisov NM, Aliper AM, Garazha AV, Rubtsov PM, Stocking C, Prassolov VS. Spirin PV, et al. Among authors: borisov nm. Leukemia. 2014 Nov;28(11):2222-8. doi: 10.1038/leu.2014.130. Epub 2014 Apr 14. Leukemia. 2014. PMID: 24727677

3

Combinatorial high-throughput experimental and bioinformatic approach identifies molecular pathways linked with the sensitivity to anticancer target drugs.

Venkova L, Aliper A, Suntsova M, Kholodenko R, Shepelin D, Borisov N, Malakhova G, Vasilov R, Roumiantsev S, Zhavoronkov A, Buzdin A. Venkova L, et al. Among authors: borisov n. Oncotarget. 2015 Sep 29;6(29):27227-38. doi: 10.18632/oncotarget.4507. Oncotarget. 2015. PMID: 26317900 Free PMC article.

4

Molecular pathway activation features linked with transition from normal skin to primary and metastatic melanomas in human.

Shepelin D, Korzinkin M, Vanyushina A, Aliper A, Borisov N, Vasilov R, Zhukov N, Sokov D, Prassolov V, Gaifullin N, Zhavoronkov A, Bhullar B, Buzdin A. Shepelin D, et al. Among authors: borisov n. Oncotarget. 2016 Jan 5;7(1):656-70. doi: 10.18632/oncotarget.6394. Oncotarget. 2016. PMID: 26624979 Free PMC article.

5

In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state.

Aliper A, Belikov AV, Garazha A, Jellen L, Artemov A, Suntsova M, Ivanova A, Venkova L, Borisov N, Buzdin A, Mamoshina P, Putin E, Swick AG, Moskalev A, Zhavoronkov A. Aliper A, et al. Among authors: borisov n. Aging (Albany NY). 2016 Sep 24;8(9):2127-2152. doi: 10.18632/aging.101047. Aging (Albany NY). 2016. PMID: 27677171 Free PMC article.

6

Data aggregation at the level of molecular pathways improves stability of experimental transcriptomic and proteomic data.

Borisov N, Suntsova M, Sorokin M, Garazha A, Kovalchuk O, Aliper A, Ilnitskaya E, Lezhnina K, Korzinkin M, Tkachev V, Saenko V, Saenko Y, Sokov DG, Gaifullin NM, Kashintsev K, Shirokorad V, Shabalina I, Zhavoronkov A, Mishra B, Cantor CR, Buzdin A. Borisov N, et al. Cell Cycle. 2017 Oct 2;16(19):1810-1823. doi: 10.1080/15384101.2017.1361068. Epub 2017 Aug 21. Cell Cycle. 2017. PMID: 28825872 Free PMC article.

7

A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency.

Borisov N, Tkachev V, Suntsova M, Kovalchuk O, Zhavoronkov A, Muchnik I, Buzdin A. Borisov N, et al. Cell Cycle. 2018;17(4):486-491. doi: 10.1080/15384101.2017.1417706. Epub 2018 Jan 17. Cell Cycle. 2018. PMID: 29251172 Free PMC article.

8

Profiling of Human Molecular Pathways Affected by Retrotransposons at the Level of Regulation by Transcription Factor Proteins.

Nikitin D, Penzar D, Garazha A, Sorokin M, Tkachev V, Borisov N, Poltorak A, Prassolov V, Buzdin AA. Nikitin D, et al. Among authors: borisov n. Front Immunol. 2018 Jan 30;9:30. doi: 10.3389/fimmu.2018.00030. eCollection 2018. Front Immunol. 2018. PMID: 29441061 Free PMC article.

9

Molecular pathway activation - New type of biomarkers for tumor morphology and personalized selection of target drugs.

Buzdin A, Sorokin M, Garazha A, Sekacheva M, Kim E, Zhukov N, Wang Y, Li X, Kar S, Hartmann C, Samii A, Giese A, Borisov N. Buzdin A, et al. Among authors: borisov n. Semin Cancer Biol. 2018 Dec;53:110-124. doi: 10.1016/j.semcancer.2018.06.003. Epub 2018 Jun 20. Semin Cancer Biol. 2018. PMID: 29935311 Review.

10

FLOating-Window Projective Separator (FloWPS): A Data Trimming Tool for Support Vector Machines (SVM) to Improve Robustness of the Classifier.

Tkachev V, Sorokin M, Mescheryakov A, Simonov A, Garazha A, Buzdin A, Muchnik I, Borisov N. Tkachev V, et al. Among authors: borisov n. Front Genet. 2019 Jan 15;9:717. doi: 10.3389/fgene.2018.00717. eCollection 2018. Front Genet. 2019. PMID: 30697229 Free PMC article.

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