Fu L - Search Results

1

Design, synthesis, and anticancer evaluation of long-chain alkoxylated mono-carbonyl analogues of curcumin.

Weng Q, Fu L, Chen G, Hui J, Song J, Feng J, Shi D, Cai Y, Ji J, Liang G. Weng Q, et al. Among authors: fu l. Eur J Med Chem. 2015 Oct 20;103:44-55. doi: 10.1016/j.ejmech.2015.08.036. Epub 2015 Aug 19. Eur J Med Chem. 2015. PMID: 26318057

2

Synthesis and biological evaluation of novel indole-2-one and 7-aza-2-oxindole derivatives as anti-inflammatory agents.

Chen G, Jiang L, Dong L, Wang Z, Xu F, Ding T, Fu L, Fang Q, Liu Z, Shan X, Liang G. Chen G, et al. Among authors: fu l. Drug Des Devel Ther. 2014 Oct 13;8:1869-92. doi: 10.2147/DDDT.S65997. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25378906 Free PMC article.

3

Discovery and evaluation of novel anti-inflammatory derivatives of natural bioactive curcumin.

Zhang Y, Jiang X, Peng K, Chen C, Fu L, Wang Z, Feng J, Liu Z, Zhang H, Liang G, Pan Z. Zhang Y, et al. Among authors: fu l. Drug Des Devel Ther. 2014 Nov 4;8:2161-71. doi: 10.2147/DDDT.S69914. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25395833 Free PMC article.

4

Synthesis and biological evaluation of novel oxindole-based RTK inhibitors as anti-cancer agents.

Chen G, Weng Q, Fu L, Wang Z, Yu P, Liu Z, Li X, Zhang H, Liang G. Chen G, et al. Among authors: fu l. Bioorg Med Chem. 2014 Dec 15;22(24):6953-60. doi: 10.1016/j.bmc.2014.10.017. Epub 2014 Oct 29. Bioorg Med Chem. 2014. PMID: 25456085

5

Discovery of a New Inhibitor of Myeloid Differentiation 2 from Cinnamamide Derivatives with Anti-Inflammatory Activity in Sepsis and Acute Lung Injury.

Chen G, Zhang Y, Liu X, Fang Q, Wang Z, Fu L, Liu Z, Wang Y, Zhao Y, Li X, Liang G. Chen G, et al. Among authors: fu l. J Med Chem. 2016 Mar 24;59(6):2436-51. doi: 10.1021/acs.jmedchem.5b01574. Epub 2016 Mar 11. J Med Chem. 2016. PMID: 26937738

6

A novel imidazopyridine derivative, X22, attenuates sepsis-induced lung and liver injury by inhibiting the inflammatory response in vitro and in vivo.

Ge X, Feng Z, Xu T, Wu B, Chen H, Xu F, Fu L, Shan X, Dai Y, Zhang Y, Liang G. Ge X, et al. Among authors: fu l. Drug Des Devel Ther. 2016 Jun 30;10:1947-59. doi: 10.2147/DDDT.S101449. eCollection 2016. Drug Des Devel Ther. 2016. PMID: 27390516 Free PMC article.

7

Synthesis and biological evaluation of allylated mono-carbonyl analogues of curcumin (MACs) as anti-cancer agents for cholangiocarcinoma.

Qiu C, Hu Y, Wu K, Yang K, Wang N, Ma Y, Zhu H, Zhang Y, Zhou Y, Chen C, Li S, Fu L, Zhang X, Liu Z. Qiu C, et al. Among authors: fu l. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5971-5976. doi: 10.1016/j.bmcl.2016.10.080. Epub 2016 Oct 28. Bioorg Med Chem Lett. 2016. PMID: 27825763

8

Discovery of new MD2-targeted anti-inflammatory compounds for the treatment of sepsis and acute lung injury.

Chen G, Xiao B, Chen L, Bai B, Zhang Y, Xu Z, Fu L, Liu Z, Li X, Zhao Y, Liang G. Chen G, et al. Among authors: fu l. Eur J Med Chem. 2017 Oct 20;139:726-740. doi: 10.1016/j.ejmech.2017.08.036. Epub 2017 Aug 24. Eur J Med Chem. 2017. PMID: 28858767

9

α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.

Chen G, Liu Y, Goetz R, Fu L, Jayaraman S, Hu MC, Moe OW, Liang G, Li X, Mohammadi M. Chen G, et al. Among authors: fu l. Nature. 2018 Jan 25;553(7689):461-466. doi: 10.1038/nature25451. Epub 2018 Jan 17. Nature. 2018. PMID: 29342138 Free PMC article.

10

Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation.

Chen L, Marsiglia WM, Chen H, Katigbak J, Erdjument-Bromage H, Kemble DJ, Fu L, Ma J, Sun G, Zhang Y, Liang G, Neubert TA, Li X, Traaseth NJ, Mohammadi M. Chen L, et al. Among authors: fu l. Nat Chem Biol. 2020 Mar;16(3):267-277. doi: 10.1038/s41589-019-0455-7. Epub 2020 Jan 20. Nat Chem Biol. 2020. PMID: 31959966 Free PMC article.

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