Thulasingam M - Search Results

1

Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase.

Kleinschmidt TK, Haraldsson M, Basavarajappa D, Lundeberg E, Thulasingam M, Ekoff M, Fauland A, Lehmann C, Kahnt AS, Lindbom L, Haeggström JZ. Kleinschmidt TK, et al. Among authors: thulasingam m. J Pharmacol Exp Ther. 2015 Oct;355(1):108-16. doi: 10.1124/jpet.115.227157. Epub 2015 Aug 17. J Pharmacol Exp Ther. 2015. PMID: 26283693

2

Trimeric microsomal glutathione transferase 2 displays one third of the sites reactivity.

Ahmad S, Thulasingam M, Palombo I, Daley DO, Johnson KA, Morgenstern R, Haeggström JZ, Rinaldo-Matthis A. Ahmad S, et al. Among authors: thulasingam m. Biochim Biophys Acta. 2015 Oct;1854(10 Pt A):1365-71. doi: 10.1016/j.bbapap.2015.06.003. Epub 2015 Jun 9. Biochim Biophys Acta. 2015. PMID: 26066610

3

Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.

Ahmad S, Ytterberg AJ, Thulasingam M, Tholander F, Bergman T, Zubarev R, Wetterholm A, Rinaldo-Matthis A, Haeggström JZ. Ahmad S, et al. Among authors: thulasingam m. J Biol Chem. 2016 Aug 26;291(35):18410-8. doi: 10.1074/jbc.M116.735647. Epub 2016 Jun 30. J Biol Chem. 2016. PMID: 27365393 Free PMC article.

4

Catalytic Conversion of Lipophilic Substrates by Phase constrained Enzymes in the Aqueous or in the Membrane Phase.

Cebula M, Turan IS, Sjödin B, Thulasingam M, Brock J, Chmyrov V, Widengren J, Abe H, Mannervik B, Haeggström JZ, Rinaldo-Matthis A, Akkaya EU, Morgenstern R. Cebula M, et al. Among authors: thulasingam m. Sci Rep. 2016 Dec 5;6:38316. doi: 10.1038/srep38316. Sci Rep. 2016. PMID: 27917951 Free PMC article.

5

Integral Membrane Enzymes in Eicosanoid Metabolism: Structures, Mechanisms and Inhibitor Design.

Thulasingam M, Haeggström JZ. Thulasingam M, et al. J Mol Biol. 2020 Aug 21;432(18):4999-5022. doi: 10.1016/j.jmb.2020.07.020. Epub 2020 Aug 1. J Mol Biol. 2020. PMID: 32745470 Review.

6

Investigation of Clozapine and Olanzapine Reactive Metabolite Formation and Protein Binding by Liquid Chromatography-Tandem Mass Spectrometry.

Geib T, Thulasingam M, Haeggström JZ, Sleno L. Geib T, et al. Among authors: thulasingam m. Chem Res Toxicol. 2020 Sep 21;33(9):2420-2431. doi: 10.1021/acs.chemrestox.0c00191. Epub 2020 Aug 17. Chem Res Toxicol. 2020. PMID: 32786547

7

Crystal structures of human MGST2 reveal synchronized conformational changes regulating catalysis.

Thulasingam M, Orellana L, Nji E, Ahmad S, Rinaldo-Matthis A, Haeggström JZ. Thulasingam M, et al. Nat Commun. 2021 Mar 19;12(1):1728. doi: 10.1038/s41467-021-21924-8. Nat Commun. 2021. PMID: 33741927 Free PMC article.

8

Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction.

Tang X, Rönnberg E, Säfholm J, Thulasingam M, Trauelsen M, Schwartz TW, Wheelock CE, Dahlén SE, Nilsson G, Haeggström JZ. Tang X, et al. Among authors: thulasingam m. Allergy. 2022 Sep;77(9):2677-2687. doi: 10.1111/all.15245. Epub 2022 Feb 14. Allergy. 2022. PMID: 35122266 Free PMC article.

9

Determining site occupancy of acetaminophen covalent binding to target proteins in vitro.

Geib T, Lento C, Marensi V, Thulasingam M, Haeggström JZ, Olsson M, Wilson DJ, Leslie EM, Sleno L. Geib T, et al. Among authors: thulasingam m. Anal Sci Adv. 2021 Mar 24;2(5-6):263-271. doi: 10.1002/ansa.202000182. eCollection 2021 Jun. Anal Sci Adv. 2021. PMID: 38716151 Free PMC article.

10

Implementation research on registering cancer cases in primary health centres of Puducherry through community health workers.

Varughese CM, Sahu SK, Karunanithi G, Duraisamy R, Sriramulu G, Raghavan B, Thulasingam M. Varughese CM, et al. Among authors: thulasingam m. Indian J Med Res. 2024 Mar & Apr;159(3 & 4):369-378. doi: 10.25259/IJMR_2285_23. Indian J Med Res. 2024. PMID: 39361801 Free PMC article.

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