El-Karef A - Search Results

1

The multi-kinase inhibitor pazopanib targets hepatic stellate cell activation and apoptosis alleviating progression of liver fibrosis.

Elshal M, Abu-Elsaad N, El-Karef A, Ibrahim TM. Elshal M, et al. Naunyn Schmiedebergs Arch Pharmacol. 2015 Dec;388(12):1293-304. doi: 10.1007/s00210-015-1157-7. Epub 2015 Aug 14. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 26269412

2

Yogurt Containing the Probacteria Lactobacillus acidophilus Combined with Natural Antioxidants Mitigates Doxorubicin-Induced Cardiomyopathy in Rats.

Abu-Elsaad NM, Abd Elhameed AG, El-Karef A, Ibrahim TM. Abu-Elsaad NM, et al. J Med Food. 2015 Sep;18(9):950-9. doi: 10.1089/jmf.2014.0104. Epub 2015 Jan 15. J Med Food. 2015. PMID: 25590792

3

The heat shock protein 90 inhibitor, 17-AAG, attenuates thioacetamide induced liver fibrosis in mice.

Abu-Elsaad NM, Serrya MS, El-Karef AM, Ibrahim TM. Abu-Elsaad NM, et al. Pharmacol Rep. 2016 Apr;68(2):275-82. doi: 10.1016/j.pharep.2015.08.015. Epub 2015 Sep 11. Pharmacol Rep. 2016. PMID: 26922527

4

Piceatannol increases the expression of hepatocyte growth factor and IL-10 thereby protecting hepatocytes in thioacetamide-induced liver fibrosis.

Abd-Elgawad H, Abu-Elsaad N, El-Karef A, Ibrahim T. Abd-Elgawad H, et al. Can J Physiol Pharmacol. 2016 Jul;94(7):779-87. doi: 10.1139/cjpp-2016-0001. Epub 2016 Mar 5. Can J Physiol Pharmacol. 2016. PMID: 27186801

5

The vitamin D receptor agonist, calcipotriol, modulates fibrogenic pathways mitigating liver fibrosis in-vivo: An experimental study.

Wahsh E, Abu-Elsaad N, El-Karef A, Ibrahim T. Wahsh E, et al. Eur J Pharmacol. 2016 Oct 15;789:362-369. doi: 10.1016/j.ejphar.2016.07.052. Epub 2016 Jul 29. Eur J Pharmacol. 2016. PMID: 27477355

6

The Falconoid Luteolin Mitigates the Myocardial Inflammatory Response Induced by High-Carbohydrate/High-Fat Diet in Wistar Rats.

Abu-Elsaad N, El-Karef A. Abu-Elsaad N, et al. Inflammation. 2018 Feb;41(1):221-231. doi: 10.1007/s10753-017-0680-8. Inflammation. 2018. PMID: 29047036

7

Gum Acacia mitigates diclofenac nephrotoxicity by targeting monocyte chemoattractant protein-1, complement receptor-1 and pro-apoptotic pathways.

Shafeek F, Abu-Elsaad N, El-Karef A, Ibrahim T. Shafeek F, et al. Food Chem Toxicol. 2019 Jul;129:162-168. doi: 10.1016/j.fct.2019.04.050. Epub 2019 Apr 28. Food Chem Toxicol. 2019. PMID: 31042592

8

Protection against nonalcoholic steatohepatitis through targeting IL-18 and IL-1alpha by luteolin.

Abu-Elsaad N, El-Karef A. Abu-Elsaad N, et al. Pharmacol Rep. 2019 Aug;71(4):688-694. doi: 10.1016/j.pharep.2019.03.009. Epub 2019 Mar 15. Pharmacol Rep. 2019. PMID: 31207429

9

Retinoic acid modulates IL-4, IL-10 and MCP-1 pathways in immune mediated hepatitis and interrupts CD4+ T cells infiltration.

Elshal M, Abu-Elsaad N, El-Karef A, Ibrahim T. Elshal M, et al. Int Immunopharmacol. 2019 Oct;75:105808. doi: 10.1016/j.intimp.2019.105808. Epub 2019 Aug 13. Int Immunopharmacol. 2019. PMID: 31419710

10

Etanercept attenuates immune-mediated hepatitis induced by concanavalin A via differential regulation of the key effector cytokines of CD4+ T cells.

Elshal M, Abu-Elsaad N, El-Karef A, Ibrahim T. Elshal M, et al. Among authors: el karef a. Life Sci. 2021 Jul 15;277:119618. doi: 10.1016/j.lfs.2021.119618. Epub 2021 May 15. Life Sci. 2021. PMID: 34004252

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