Knapp S - Search Results

1

CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses.

Hammitzsch A, Tallant C, Fedorov O, O'Mahony A, Brennan PE, Hay DA, Martinez FO, Al-Mossawi MH, de Wit J, Vecellio M, Wells C, Wordsworth P, Müller S, Knapp S, Bowness P. Hammitzsch A, et al. Among authors: knapp s. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10768-73. doi: 10.1073/pnas.1501956112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261308 Free PMC article.

2

Thermodynamics of HMGB1 interaction with duplex DNA.

Müller S, Bianchi ME, Knapp S. Müller S, et al. Among authors: knapp s. Biochemistry. 2001 Aug 28;40(34):10254-61. doi: 10.1021/bi0100900. Biochemistry. 2001. PMID: 11513603

3

The long acidic tail of high mobility group box 1 (HMGB1) protein forms an extended and flexible structure that interacts with specific residues within and between the HMG boxes.

Knapp S, Müller S, Digilio G, Bonaldi T, Bianchi ME, Musco G. Knapp S, et al. Biochemistry. 2004 Sep 28;43(38):11992-7. doi: 10.1021/bi049364k. Biochemistry. 2004. PMID: 15379539

4

Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.

Bullock AN, Debreczeni JE, Fedorov OY, Nelson A, Marsden BD, Knapp S. Bullock AN, et al. Among authors: knapp s. J Med Chem. 2005 Dec 1;48(24):7604-14. doi: 10.1021/jm0504858. J Med Chem. 2005. PMID: 16302800

5

Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.

Bullock AN, Debreczeni JE, Edwards AM, Sundström M, Knapp S. Bullock AN, et al. Among authors: knapp s. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7637-42. doi: 10.1073/pnas.0601638103. Epub 2006 May 4. Proc Natl Acad Sci U S A. 2006. PMID: 16675548 Free PMC article.

6

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.

Kavanagh KL, Guo K, Dunford JE, Wu X, Knapp S, Ebetino FH, Rogers MJ, Russell RG, Oppermann U. Kavanagh KL, et al. Among authors: knapp s. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7829-34. doi: 10.1073/pnas.0601643103. Epub 2006 May 9. Proc Natl Acad Sci U S A. 2006. PMID: 16684881 Free PMC article.

7

Structure and regulation of the human Nek2 centrosomal kinase.

Rellos P, Ivins FJ, Baxter JE, Pike A, Nott TJ, Parkinson DM, Das S, Howell S, Fedorov O, Shen QY, Fry AM, Knapp S, Smerdon SJ. Rellos P, et al. Among authors: knapp s. J Biol Chem. 2007 Mar 2;282(9):6833-42. doi: 10.1074/jbc.M609721200. Epub 2006 Dec 31. J Biol Chem. 2007. PMID: 17197699 Free article.

8

Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs.

Eswaran J, Lee WH, Debreczeni JE, Filippakopoulos P, Turnbull A, Fedorov O, Deacon SW, Peterson JR, Knapp S. Eswaran J, et al. Among authors: knapp s. Structure. 2007 Feb;15(2):201-13. doi: 10.1016/j.str.2007.01.001. Structure. 2007. PMID: 17292838 Free PMC article.

9

Insights for the development of specific kinase inhibitors by targeted structural genomics.

Fedorov O, Sundström M, Marsden B, Knapp S. Fedorov O, et al. Among authors: knapp s. Drug Discov Today. 2007 May;12(9-10):365-72. doi: 10.1016/j.drudis.2007.03.006. Epub 2007 Mar 29. Drug Discov Today. 2007. PMID: 17467572 Review.

10

The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.

Gileadi O, Knapp S, Lee WH, Marsden BD, Müller S, Niesen FH, Kavanagh KL, Ball LJ, von Delft F, Doyle DA, Oppermann UC, Sundström M. Gileadi O, et al. Among authors: knapp s. J Struct Funct Genomics. 2007 Sep;8(2-3):107-19. doi: 10.1007/s10969-007-9027-2. Epub 2007 Oct 12. J Struct Funct Genomics. 2007. PMID: 17932789 Free PMC article. Review.

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