Knüchel R - Search Results

1

Low expression of ITIH5 in adenocarcinoma of the lung is associated with unfavorable patients' outcome.

Dötsch MM, Kloten V, Schlensog M, Heide T, Braunschweig T, Veeck J, Petersen I, Knüchel R, Dahl E. Dötsch MM, et al. Among authors: knuchel r. Epigenetics. 2015;10(10):903-12. doi: 10.1080/15592294.2015.1078049. Epub 2015 Aug 7. Epigenetics. 2015. PMID: 26252352 Free PMC article.

2

Paradox of sonic hedgehog (SHH) transcriptional regulation: Alternative transcription initiation overrides the effect of downstream promoter DNA methylation.

ten Haaf A, Franken L, Heymann C, von Serenyi S, Cornelissen C, de Hoon JP, Veeck J, Lüscher B, Knüchel R, Dahl E. ten Haaf A, et al. Among authors: knuchel r. Epigenetics. 2011 Apr;6(4):465-77. doi: 10.4161/epi.6.4.14952. Epub 2011 Apr 1. Epigenetics. 2011. PMID: 21372638

3

Epigenetic inactivation of the novel candidate tumor suppressor gene ITIH5 in colon cancer predicts unfavorable overall survival in the CpG island methylator phenotype.

Kloten V, Rose M, Kaspar S, von Stillfried S, Knüchel R, Dahl E. Kloten V, et al. Among authors: knuchel r. Epigenetics. 2014 Sep;9(9):1290-301. doi: 10.4161/epi.32089. Epub 2014 Aug 4. Epigenetics. 2014. PMID: 25093535 Free PMC article.

4

OASIS/CREB3L1 is epigenetically silenced in human bladder cancer facilitating tumor cell spreading and migration in vitro.

Rose M, Schubert C, Dierichs L, Gaisa NT, Heer M, Heidenreich A, Knüchel R, Dahl E. Rose M, et al. Among authors: knuchel r. Epigenetics. 2014 Dec;9(12):1626-40. doi: 10.4161/15592294.2014.988052. Epigenetics. 2014. PMID: 25625847 Free PMC article.

5

Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients' Outcome in Basal-Like Breast Cancer.

Kloten V, Schlensog M, Eschenbruch J, Gasthaus J, Tiedemann J, Mijnes J, Heide T, Braunschweig T, Knüchel R, Dahl E. Kloten V, et al. Among authors: knuchel r. PLoS One. 2016 Jul 11;11(7):e0159073. doi: 10.1371/journal.pone.0159073. eCollection 2016. PLoS One. 2016. PMID: 27400234 Free PMC article.

6

Epigenetic loss of putative tumor suppressor SFRP3 correlates with poor prognosis of lung adenocarcinoma patients.

Schlensog M, Magnus L, Heide T, Eschenbruch J, Steib F, Tator M, Kloten V, Rose M, Noetzel E, Gaisa NT, Knüchel R, Dahl E. Schlensog M, et al. Among authors: knuchel r. Epigenetics. 2018;13(3):214-227. doi: 10.1080/15592294.2016.1229730. Epub 2018 Apr 18. Epigenetics. 2018. PMID: 27623992 Free PMC article.

7

ITIH5 mediates epigenetic reprogramming of breast cancer cells.

Rose M, Kloten V, Noetzel E, Gola L, Ehling J, Heide T, Meurer SK, Gaiko-Shcherbak A, Sechi AS, Huth S, Weiskirchen R, Klaas O, Antonopoulos W, Lin Q, Wagner W, Veeck J, Gremse F, Steitz J, Knüchel R, Dahl E. Rose M, et al. Among authors: knuchel r. Mol Cancer. 2017 Feb 23;16(1):44. doi: 10.1186/s12943-017-0610-2. Mol Cancer. 2017. PMID: 28231808 Free PMC article.

8

ITIH5 induces a shift in TGF-β superfamily signaling involving Endoglin and reduces risk for breast cancer metastasis and tumor death.

Rose M, Meurer SK, Kloten V, Weiskirchen R, Denecke B, Antonopoulos W, Deckert M, Knüchel R, Dahl E. Rose M, et al. Among authors: knuchel r. Mol Carcinog. 2018 Feb;57(2):167-181. doi: 10.1002/mc.22742. Epub 2017 Oct 30. Mol Carcinog. 2018. PMID: 28940371

9

Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer.

Mijnes J, Veeck J, Gaisa NT, Burghardt E, de Ruijter TC, Gostek S, Dahl E, Pfister D, Schmid SC, Knüchel R, Rose M. Mijnes J, et al. Among authors: knuchel r. Clin Epigenetics. 2018 Feb 6;10:15. doi: 10.1186/s13148-018-0447-6. eCollection 2018. Clin Epigenetics. 2018. PMID: 29445424 Free PMC article.

10

The ECM Modulator ITIH5 Affects Cell Adhesion, Motility and Chemotherapeutic Response of Basal/Squamous-Like (BASQ) Bladder Cancer Cells.

Rose M, Noetzel E, Kistermann J, Eschenbruch J, Rushrush S, Gan L, Knüchel R, Gaisa NT, Dahl E. Rose M, et al. Among authors: knuchel r. Cells. 2021 Apr 28;10(5):1038. doi: 10.3390/cells10051038. Cells. 2021. PMID: 33924987 Free PMC article.

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